Insoluble versus soluble polymer-assisted synthesis.: A first approach for the preparation of a Biginelli compound

被引：5

作者：

Vanden Eynde, JJ ^{[1
]}

Watté, O

机构：

[1] Xavier Univ, Coll Pharm, Div Basic Pharmaceut Sci, 1 Drexel Dr, New Orleans, LA 70125 USA

[2] Univ Mons, Dept Organ Chem, Fac Sci, B-7000 Mons, Belgium

来源：

ARKIVOC | 2003年

关键词：

solid-phase synthesis; liquid-phase synthesis; dendrimer; pyrimidine; Biginelli;

D O I：

10.3998/ark.5550190.0004.408

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A comparison is established between the experimental conditions associated with the multistep synthesis of ethyl 1,2,3,4-tetrahydro-6-methyl-2-oxo-4-phenylpyrimidine-5-carboxylate from Merrifield's resin and soluble polymers, derived from poly( ethylene glycol), poly( styrene-co-allyl alcohol), or dendritic aliphatic polyols.

引用

页码：93 / 101

页数：9

共 14 条

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