Incorporation of an Allogenic Cortical Bone Graft Following Arthrodesis of the First Metatarsophalangeal Joint in a Patient with Hallux Rigidus

被引:12
作者
Brcic, Iva [1 ]
Pastl, Klaus [2 ]
Plank, Harald [3 ]
Igrec, Jasminka [4 ]
Schanda, Jakob E. [5 ,6 ,7 ]
Pastl, Eva [2 ]
Werner, Mathias [8 ]
机构
[1] Med Univ Graz, Diagnost & Res Inst Pathol, A-8010 Graz, Austria
[2] Diakonissen Hosp Linz, Dept Orthoped Surg, A-4020 Linz, Austria
[3] Graz Ctr Electron Microscopy, A-8010 Graz, Austria
[4] Med Univ Graz, Dept Radiol, Div Gen Radiol, A-8036 Graz, Austria
[5] AUVA Trauma Ctr Vienna Meidling, Dept Trauma Surg, A-1120 Vienna, Austria
[6] Ludwig Boltzmann Inst Expt & Clin Traumatol, A-1200 Vienna, Austria
[7] Austrian Cluster Tissue Regenerat, A-1200 Vienna, Austria
[8] VIVANTES Netzwerk Gesundheit, FB Pathol, Osteopathol, D-13407 Berlin, Germany
来源
LIFE-BASEL | 2021年 / 11卷 / 06期
关键词
hallux rigidus; allogenic; cortical bone graft; screw; arthrodesis; ALLOGRAFTS; IMPLANT;
D O I
10.3390/life11060473
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Hallux rigidus is degenerative arthritis of the first metatarsophalangeal joint characterized by pain and stiffness in the joint with limitation of motion and functional impairment. Recently, bone grafts have been introduced in orthopedic procedures, namely osteosynthesis and arthrodesis. Allografts can induce bone formation, provide support for vascular and bone ingrowth and have a low risk of immunological rejection. A 52-year-old female patient with hallux rigidus underwent arthrodesis of the first metatarsophalangeal joint using Shark Screw(R) made of allogenic cortical bone. Corrective surgery was performed after 10 weeks, and a 5 x 3 mm large part of the Shark Screw(R) with the surrounding patient's bone was removed. A histological evaluation revealed a vascularized graft with the newly formed compact lamellar bone fitting exactly to the cortical graft. The bone surface was lined by plump osteoblasts with osteoid production, and osteocytes were present in the lacunae. The arthrodesis of the first metatarsophalangeal joint using an allogenic cortical bone graft results in fast, primary bone healing without immunological rejection. This case suggests that the cortical allograft is a good and safe treatment option with an excellent graft incorporation into the host bone. However, as the literature evaluating the histology of different bone grafts is scarce, further high-level evidence studies with adequate sample sizes are needed to confirm our findings.
引用
收藏
页数:8
相关论文
共 22 条
[1]   Osteoinduction, osteoconduction and osseointegration [J].
Albrektsson, T ;
Johansson, C .
EUROPEAN SPINE JOURNAL, 2001, 10 (Suppl 2) :S96-S101
[2]   Autograft, Allograft, and Bone Graft Substitutes: Clinical Evidence and Indications for Use in the Setting of Orthopaedic Trauma Surgery [J].
Baldwin, Paul ;
Li, Deborah J. ;
Auston, Darryl A. ;
Mir, Hassan S. ;
Yoon, Richard S., II ;
Koval, Kenneth J. .
JOURNAL OF ORTHOPAEDIC TRAUMA, 2019, 33 (04) :203-213
[3]  
Böstman OM, 2000, CLIN ORTHOP RELAT R, P216
[4]   Quantifying Vascular Changes Surrounding Bone Regeneration in a Porcine Mandibular Defect Using Computed Tomography [J].
Carlisle, Patricia ;
Marrs, Jeffrey ;
Gaviria, Laura ;
Silliman, David T. ;
Decker, John F. ;
Baer, Pamela Brown ;
Guda, Teja .
TISSUE ENGINEERING PART C-METHODS, 2019, 25 (12) :721-731
[5]  
Dillard Sarita, 2018, J Am Podiatr Med Assoc, DOI 10.7547/16-126
[6]   Retrieved human allografts - A clinicopathological study [J].
Enneking, WE ;
Campanacci, DA .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 2001, 83A (07) :971-986
[7]   OBSERVATIONS ON MASSIVE RETRIEVED HUMAN ALLOGRAFTS [J].
ENNEKING, WF ;
MINDELL, ER .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1991, 73A (08) :1123-1142
[8]   First Metatarsophalangeal Arthrodesis for Hallux Rigidus [J].
Fuhrmann, Renee A. .
FOOT AND ANKLE CLINICS, 2011, 16 (01) :1-12
[9]   Osteoinductive biomaterials - properties and relevance in bone repair [J].
Habibovic, Pamela ;
de Groot, Klaas .
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 2007, 1 (01) :25-32
[10]   Angiogenesis in bone regeneration [J].
Hankenson, Kurt D. ;
Dishowitz, Michael ;
Gray, Chancellor ;
Schenker, Mara .
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 2011, 42 (06) :556-561