Perioperative Anaphylaxis

被引：107

作者：

Mertes, P. M. ^{[1
,2
]}

Tajima, K. ^{[1
,2
]}

Regnier-Kimmoun, M. A. ^{[1
,2
]}

Lambert, M. ^{[1
,3
]}

Iohom, G. ^{[4
]}

Gueant-Rodriguez, R. M. ^{[5
,6
]}

Malinovsky, J. M. ^{[7
]}

机构：

[1] CHU Nancy, Serv Anesthesie Reanimat Chirurg, Hop Cent, F-54035 Nancy, France

[2] Fac Med Vandoeuvre Nancy, INSERM, U911, F-54505 Vandoeuvre Les Nancy, France

[3] Fac Med Vandoeuvre Nancy, INSERM, U684, F-54505 Vandoeuvre Les Nancy, France

[4] Natl Univ Ireland Univ Coll Cork, Cork Univ Hosp, Dept Anaesthesia & Intens Care Med, Cork, Ireland

[5] CHU Brabois, Lab Biochim Biol Mol Nutr Metab, F-54511 Vandoeuvre Les Nancy, France

[6] Fac Med Vandoeuvre Nancy, Unite Pathol Cellulaire & Mol Nutr, U724, INSERM, F-54505 Vandoeuvre Les Nancy, France

[7] Hop Maison Blanche, Pole URAD, CHU Reims, Serv Anesthesie & Reanimat, F-51092 Reims, France

来源：

MEDICAL CLINICS OF NORTH AMERICA | 2010年 / 94卷 / 04期

关键词：

Anesthesia; Anaphylaxis; Tryptase; Skin test; Neuromuscular blocking agent; Latex; Antibiotics; Epinephrine; MUSCLE-RELAXANT DRUGS; NEUROMUSCULAR BLOCKING-AGENTS; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; LATEX-ALLERGY DIAGNOSIS; BASOPHIL ACTIVATION; IGE-ANTIBODIES; FOLLOW-UP; IN-VITRO; HYPERSENSITIVITY REACTIONS; REVISED NOMENCLATURE;

D O I：

10.1016/j.mcna.2010.04.002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The incidence of immune-mediated anaphylaxis during anesthesia ranges from 1 in 10,000 to 1 in 20,000. Neuromuscular blocking agents are most frequently incriminated, followed by latex and antibiotics, although any drug or substance used may be a culprit. Diagnosis relies on tryptase measurements at the time of the reaction and skin tests, specific immunoglobulin E, or basophil activation assays. Treatment consists of rapid volume expansion and epinephrine administration titrated to symptom severity.

引用

页码：761 / +

页数：30

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