Prognostic Impact and Therapeutic Implications of Sentinel Lymph Node Micro-Metastases in Early-Stage Breast Cancer Patients

被引：10

作者：

Viehl, Carsten T. ^{[4
]}

Langer, Igor ^{[4
]}

Guller, Ulrich ^{[4
]}

Zanetti-Daellenbach, Rosanna ^{[3
]}

Moch, Holger ^{[2
]}

Wight, Edward ^{[3
]}

Oertli, Daniel ^{[4
]}

Zuber, Markus ^{[1
]}

机构：

[1] Kantonsspital Olten, Dept Surg, CH-4600 Olten, Switzerland

[2] Univ Zurich Hosp, Dept Pathol, CH-8091 Zurich, Switzerland

[3] Univ Basel Hosp, Dept Gynecol, CH-4031 Basel, Switzerland

[4] Univ Basel Hosp, Dept Surg, CH-4031 Basel, Switzerland

来源：

JOURNAL OF SURGICAL ONCOLOGY | 2011年 / 103卷 / 06期

关键词：

breast cancer; axillary lymph node dissection; sentinel lymph node procedure; lymphatic micrometastasis; treatment outcome; COMPLETION AXILLARY DISSECTION; INTERNATIONAL CONSENSUS PANEL; MICROMETASTASES; BIOPSY; RECURRENCE; HIGHLIGHTS; RATES; SLN;

D O I：

10.1002/jso.21693

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The prognostic value of sentinel lymph node (SLN) micro-metastases and the question whether patients with SLN micro-metastases should undergo axillary lymph node dissection remain a matter of great debate. Based on the current literature and on our own data, we provide suggestive evidence that SLN micro-metastases in early stage breast cancer patients appear to have prognostic value and should impact the decision-making regarding adjuvant therapy, however, do not necessarily require further surgical treatment. J. Surg. Oncol. 2011;103:531-533. (C) 2011 Wiley-Liss, Inc.

引用

页码：531 / 533

页数：3

共 25 条

[1] Comparison of Commission on Cancer-Approved and -Nonapproved Hospitals in the United States: Implications for Studies That Use the National Cancer Data Base [J].

Bilimoria, Karl Y. ;

Bentrem, David J. ;

Stewart, Andrew K. ;

Winchester, David P. ;

Ko, Clifford Y. .

JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (25) :4177-4181

[2]

Carlo John T, 2005, Proc (Bayl Univ Med Cent), V18, P103

[3] Clinical outcome of patients with lymph node-negative breast carcinoma who have sentinel lymph node micrometastases detected by immunohistochemistry [J].

Chagpar, A ;

Middleton, LP ;

Sahin, AA ;

Meric-Bernstam, F ;

Kuerer, HM ;

Feig, BW ;

Ross, MI ;

Ames, FC ;

Singletary, SE ;

Buchholz, TA ;

Valero, V ;

Hunt, KK .

CANCER, 2005, 103 (08) :1581-1586

[4] Micrometastases or Isolated Tumor Cells and the Outcome of Breast Cancer [J].

de Boer, Maaike ;

van Deurzen, Carolien H. M. ;

van Dijck, Jos A. A. M. ;

Borm, George F. ;

van Diest, Paul J. ;

Adang, Eddy M. M. ;

Nortier, Johan W. R. ;

Rutgers, Emiel J. T. ;

Seynaeve, Caroline ;

Menke-Pluymers, Marian B. E. ;

Bult, Peter ;

Tjan-Heijnen, Vivianne C. G. .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (07) :653-663

[5] The effect of sentinel node tumor burden on non-sentinel node status and recurrence rates in breast cancer [J].

Fan, YG ;

Tan, YY ;

Wu, CT ;

Treseler, P ;

Lu, Y ;

Chan, CW ;

Hwang, S ;

Ewing, C ;

Esserman, L ;

Morita, E ;

Leong, SPL .

ANNALS OF SURGICAL ONCOLOGY, 2005, 12 (09) :705-711

[6] Preliminary outcome analysis in patients with breast cancer and a positive sentinel lymph node who declined axillary dissection [J].

Fant, JS ;

Grant, MD ;

Knox, SM ;

Livingston, SA ;

Ridl, K ;

Jones, RC ;

Kuhn, JA .

ANNALS OF SURGICAL ONCOLOGY, 2003, 10 (02) :126-130

[7] Micrometastasis in the sentinel lymph node of breast cancer does not mandate completion axillary dissection [J].

Fournier, K ;

Schiller, A ;

Perry, RR ;

Laronga, C .

ANNALS OF SURGERY, 2004, 239 (06) :859-863

[8]

Ganaraj Archana, 2003, Proc (Bayl Univ Med Cent), V16, P3

[9] Locoregional Recurrence After Sentinel Lymph Node Dissection With or Without Axillary Dissection in Patients With Sentinel Lymph Node Metastases [J].

Giuliano, Armando E. ;

McCall, Linda ;

Beitsch, Peter ;

Whitworth, Pat W. ;

Blumencranz, Peter ;

Leitch, A. Marilyn ;

Saha, Sukamal ;

Hunt, Kelly K. ;

Morrow, Monica ;

Ballman, Karla .

ANNALS OF SURGERY, 2010, 252 (03) :426-433

[10] Axillary Dissection vs No Axillary Dissection in Women With Invasive Breast Cancer and Sentinel Node Metastasis A Randomized Clinical Trial [J].

Giuliano, Armando E. ;

Hunt, Kelly K. ;

Ballman, Karla V. ;

Beitsch, Peter D. ;

Whitworth, Pat W. ;

Blumencranz, Peter W. ;

Leitch, A. Marilyn ;

Saha, Sukamal ;

McCall, Linda M. ;

Morrow, Monica .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2011, 305 (06) :569-575

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