Effective eculizumab therapy followed by BMT in a boy with paroxysmal nocturnal hemoglobinuria

被引：1

作者：

Oshiro, Hiroko ^{[1
]}

Goi, Kumiko ^{[1
]}

Akahane, Koshi ^{[1
]}

Inukai, Takeshi ^{[1
]}

Sugita, Kanji ^{[1
]}

机构：

[1] Univ Yamanashi, Dept Pediat, Sch Med, Kofu, Yamanashi 4093898, Japan

来源：

PEDIATRICS INTERNATIONAL | 2015年 / 57卷 / 02期

关键词：

bone marrow transplantation; eculizumab; paroxysmal nocturnal hemoglobinuria; HEMATOPOIETIC-CELL TRANSPLANTATION; PNH;

D O I：

10.1111/ped.12522

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

A 9-year-old boy with paroxysmal nocturnal hemoglobinuria/aplastic anemia syndrome (PNH/AA) developed hemolytic crisis after receiving immunosuppressive therapy. Eculizumab dramatically relieved the signs and symptoms and then he safely underwent unrelated bone marrow transplantation, suggesting the feasibility and effectiveness of eculizumab before stem cell transplantation in children with PNH/AA in hemolytic crisis.

引用

页码：e27 / e29

页数：3

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