Travelers Can Import Colistin-Resistant Enterobacteriaceae, Including Those Possessing the Plasmid-Mediated mcr-1 Gene

被引：74

作者：

Bernasconi, Odette J. ^{[1
,2
]}

Kuenzli, Esther ^{[3
,4
]}

Pires, Joao ^{[1
,2
]}

Tinguely, Regula ^{[1
]}

Carattoli, Alessandra ^{[1
,5
]}

Hatz, Christoph ^{[3
,4
]}

Perreten, Vincent ^{[6
]}

Endimiani, Andrea ^{[1
]}

机构：

[1] Univ Bern, Inst Infect Dis, Bern, Switzerland

[2] Univ Bern, Grad Sch Cellular & Biomed Sci, Bern, Switzerland

[3] Swiss Trop & Publ Hlth Inst, Basel, Switzerland

[4] Univ Zurich, Inst Social & Prevent Med, Div Communicable Dis, Zurich, Switzerland

[5] Ist Super Sanita, Dept Infect Parasit & Immune Mediated Dis, Rome, Italy

[6] Univ Bern, Vetsuisse Fac, Inst Vet Bacteriol, Bern, Switzerland

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2016年 / 60卷 / 08期

关键词：

SPECTRUM-BETA-LACTAMASE; ESCHERICHIA-COLI; CARBAPENEM-RESISTANT; IDENTIFICATION; DISSEMINATION; EPIDEMIOLOGY; EMERGENCE;

D O I：

10.1128/AAC.00731-16

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Stool samples from 38 travelers returning from India were screened for extended-spectrum cephalosporin- and carbapenem-resistant Enterobacteriaceae implementing standard selective plates. Twenty-six (76.3%) people were colonized with CTX-M or DHA producers, but none of the strains was colistin resistant and/or mcr-1 positive. Nevertheless, using overnight enrichment and CHROMagar Orientation plates supplemented with colistin, four people (10.5%) were found to be colonized with colistin-resistant Escherichia coli. One cephalosporin-susceptible sequence type 10 (ST10) strain carried a 4,211-bp ISApl1-mcr-1-ISApl1 element in an IncHI2 plasmid backbone.

引用

页码：5080 / 5084

页数：5

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