Management of Thymic Tumors A Survey of Current Practice among Members of the European Society of Thoracic Surgeons

被引:79
作者
Ruffini, Enrico [1 ]
Van Raemdonck, Dirk [2 ]
Detterbeck, Frank [3 ]
Rocco, Gaetano [4 ]
Thomas, Pascal [5 ,6 ]
Venuta, Federico [7 ]
机构
[1] Univ Turin, Dept Thorac Surg, Turin, Italy
[2] Univ Hosp Leuven, Dept Thorac Surg, Louvain, Belgium
[3] Yale Univ, Dept Thorac Surg, New Haven, CT USA
[4] Pascale Fdn, Natl Canc Inst, Dept Thorac Surg, Naples, Italy
[5] Univ Mediterranean, N Univ Hosp, Dept Thorac Surg, Marseille, France
[6] Univ Hosp Syst Marseille, Marseille, France
[7] Univ Roma La Sapienza, Policlin Umberto I, Dept Thorac Surg, Rome, Italy
关键词
Thymoma; Thymic carcinoma; Surgery; Survey; SURGICAL-TREATMENT; INVASIVE THYMOMA; MULTIMODALITY TREATMENT; EPITHELIAL NEOPLASMS; NONINVASIVE THYMOMA; PLEURAL RECURRENCE; COMPLETE RESECTION; PROGNOSTIC-FACTORS; INTERGROUP TRIAL; CLASSIFICATION;
D O I
10.1097/JTO.0b013e318207cd74
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Introduction: Management of thymoma has largely been based on single-institution retrospective, observational studies. The European Society of Thoracic Surgeons (ESTS) Thymic Working Group has investigated the current practice among ESTS members. Methods: A questionnaire divided into seven sections with 24 questions was designed, and it was delivered to ESTS members. Results: Forty-four centers replied to the questionnaire. The results indicate that there is a general agreement concerning (1) the value of computed tomography scan for preoperative assessment; (2) the uselessness of a routine histologic confirmation before surgery; (3) the role of the World Health Organization classification; (4) the importance of complete and extended resection; (5) the role of surgery for recurrent disease; and (6) the need of a multidisciplinary team, including thoracic surgeons, pathologists, medical, and radiation oncologists. On the other hand, there is still a considerable debate about (1) the role of positron emission tomography scan for preoperative assessment; (2) a consistent and reliable staging system; (3) the usefulness of postoperative treatments for stages II and III diseases; (4) the management of type C thymoma; and (5) the role of extrapleural pneumonectomy for stage IVA thymoma. Conclusions: The survey provides a large, multiinstitutional overview of the clinical practice in the management of thymic tumors by ESTS members. Responses show some areas of agreement along with several areas of controversy. It is conceivable that a consequent step forward will be the creation of a collaborative effort within the ESTS and with other organizations for the creation of standard recommendations and guidelines for the management of thymic malignancies.
引用
收藏
页码:614 / 623
页数:10
相关论文
共 54 条
  • [1] [Anonymous], WORLD HLTH ORG CLASS
  • [2] Predictors of survival in patients with locally advanced thymoma and thymic carcinoma (Masaoka stages III and IVa)
    Cardillo, Giuseppe
    Carleo, Francesco
    Giunti, Roberto
    Lopergolo, Michele Giovanni
    Salvadori, Lorenzo
    De Massimi, Alessia Raffaella
    Petrella, Lea
    Martelli, Massimo
    [J]. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2010, 37 (04) : 819 - 823
  • [3] Correlation of the WHO schema for the classification of thymic epithelial neoplasms with prognosis - A retrospective study of 90 tumors
    Chalabreysse, L
    Roy, P
    Cordier, JF
    Loire, R
    Gamondes, JP
    Thivolet-Bejui, F
    [J]. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2002, 26 (12) : 1605 - 1611
  • [4] INVASIVE THYMOMA - THE ROLE OF MEDIASTINAL IRRADIATION FOLLOWING COMPLETE OR INCOMPLETE SURGICAL RESECTION
    CURRAN, WJ
    KORNSTEIN, MJ
    BROOKS, JJ
    TURRISI, AT
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 1988, 6 (11) : 1722 - 1727
  • [5] The role of surgery in the management of thymoma: A systematic review
    Davenport, Eric
    Malthaner, Richard A.
    [J]. ANNALS OF THORACIC SURGERY, 2008, 86 (02) : 673 - 684
  • [6] Extended operation for recurrent thymic carcinoma presenting with intracaval growth and intracardiac extension
    De Giacomo, Tiziano
    Mazzesi, Giuseppe
    Venuta, Federico
    Coloni, G. F.
    [J]. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2007, 134 (05) : 1364 - 1365
  • [7] Thymic tumors
    Detterbeck, FC
    Parsons, AM
    [J]. ANNALS OF THORACIC SURGERY, 2004, 77 (05) : 1860 - 1869
  • [8] Egan TM, 1997, ANN THORAC SURG, V64, P1591
  • [9] Malignant thymoma in the United States: Demographic patterns in incidence and associations with subsequent malignancies
    Engels, EA
    Pfeiffer, RM
    [J]. INTERNATIONAL JOURNAL OF CANCER, 2003, 105 (04) : 546 - 551
  • [10] 17 YEARS OF SURGICAL-TREATMENT OF THYMOMA - FACTORS INFLUENCING SURVIVAL
    GAMONDES, JP
    BALAWI, A
    GREENLAND, T
    ADLEINE, P
    MORNEX, JF
    ZHANG, J
    MARET, G
    [J]. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 1991, 5 (03) : 124 - 131