Role of surgery (cytoreductive nephrectomy and metastasectomy) in the management of metastatic renal cell carcinoma: A literature review

被引：1
|
作者：
Arroua, F. [1 ]
Maurin, C. [1 ]
Carcenac, A. [1 ]
Ragni, E. [1 ]
Rossi, D. [1 ]
Bastide, C. [1 ]
机构：
[1] CHU Nord Marseille, Serv Urol, F-13915 Marseille 20, France
来源：
PROGRES EN UROLOGIE | 2010年 / 20卷 / 13期
关键词：
Cytoreductive nephrectorny; Metastatic renal cell carcinoma; Metastasectorny; Targeted therapy; TYROSINE KINASE INHIBITORS; NEPHRON-SPARING SURGERY; SYSTEMIC THERAPY; INTERFERON-ALPHA; PROGNOSTIC-FACTORS; SPONTANEOUS REGRESSION; STRATIFICATION TOOL; SCORING ALGORITHM; PREDICT SURVIVAL; PRIMARY TUMOR;
D O I：
10.1016/j.purol.2010.06.001
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Cytoreductive nephrectomy is an established treatment option prior immunotherapy in well-selected patients with metastatic renal cell carcinoma. With the recent introduction of new targeted agents, the role of surgery has been source of controversy. This review examines the role of cytoreductive nephrectomy during the immunotherapy era, then in the new targeted therapies era. This review also summarizes the optimal timing of these treatments, the prognostic factors predicting outcome following cytoreductive nephrectomy, the role of metastasectomy, partial and laparoscopic cytoreductive nephrectomy. (c) 2010 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：1175 / 1183
页数：9
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