The Detection of Osthole and Application of Cell Imaging Based on Nitrogen-Doped Carbon Dots

被引：5

作者：

Wang, Ning ^{[1
]}

Yang, Xuefang ^{[1
]}

Wang, Haojiang ^{[1
]}

Xie, Liping ^{[2
]}

Jia, Weihua ^{[2
]}

Bian, Wei ^{[1
]}

Choi, Martin M. F. ^{[3
]}

机构：

[1] Shanxi Med Univ, Sch Basic Med Sci, Taiyuan 030001, Peoples R China

[2] Sixth Hosp Shanxi Med Univ, Gen Hosp Tisco, Taiyuan 030001, Peoples R China

[3] Bristol Chinese Christian Church, Tyndale Baptist Church, 137-139 Whiteladies Rd, Bristol BS8 2QG, Avon, England

来源：

NANO | 2020年 / 15卷 / 02期

关键词：

Fluorescence probe; nitrogen-doped carbon dots; osthole; biological samples; cell imaging; QUANTUM DOTS; FLUORESCENT-PROBE; SELECTIVE DETECTION; ASCORBIC-ACID; EMISSION; SYSTEM; HG2+;

D O I：

10.1142/S1793292020500253

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

A fluorescence probe has been synthesized for the detection of osthole using the nitrogen-doped carbon dots (NCDs) as shown in Fig. 1. The NCDs were fully characterized by transmission electron microscopy (TEM), X-ray diffraction (XRD), x-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR). Under the optimal experimental conditions, the NCDs fluorescence probe was highly selective and sensitive to osthole. The linear response range for osthole was 5.0-75 mu M with a detection limit of 38 nM. The mechanism of the interaction of osthole and NCDs was discussed. The fluorescence probe has been applied to the analysis of biological samples. The as-synthesized NCDs with high fluorescence intensity, low toxicity and good biocompatibility were applied to cell imaging.

引用

页数：12

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