Micrographia after thalamomesencephalic infarction:: Evidence of striatal dopaminergic hypofunction

被引：21

作者：

Kim, JS ^{[1
]}

Im, JH ^{[1
]}

Kwon, SU ^{[1
]}

Kang, JH ^{[1
]}

Lee, MC ^{[1
]}

机构：

[1] Univ Ulsan, Asan Med Ctr, Dept Neurol, Seoul 138600, South Korea

来源：

NEUROLOGY | 1998年 / 51卷 / 02期

关键词：

D O I：

10.1212/WNL.51.2.625

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A patient with left thalamo-mesencephalic infarction presented with micrographia in the right hand as the only motor sign. Brain MRI and Tc-99m ethyl cysteinate dimer (ECD) perfusion SPECT revealed ischemic lesions in the left midbrain and the anterior thalamus, but not in the basal ganglia, whereas [I-123]-IPT SPECT demonstrated decreased activity of the [I-123]-IPT in the left striatum. The patient's micrographia may be related to a dysfunctional nigrostriatal dopaminergic system secondary to ischemic damage to the substantia nigra.

引用

页码：625 / 627

页数：3

共 10 条

[1]

Abe K, 1996, NEURORADIOLOGY, V38, pS67

[2] PURE MIDBRAIN INFARCTION - CLINICAL SYNDROMES, MRI, AND ETIOLOGIC PATTERNS [J].

BOGOUSSLAVSKY, J ;

MAEDER, P ;

REGLI, F ;

MEULI, R .

NEUROLOGY, 1994, 44 (11) :2032-2040

[3] Head tremor and stroke [J].

Kim, JS .

CEREBROVASCULAR DISEASES, 1997, 7 (03) :175-179

[4] MOVEMENT-DISORDERS FOLLOWING LESIONS OF THE THALAMUS OR SUBTHALAMIC REGION [J].

LEE, MS ;

MARSDEN, CD .

MOVEMENT DISORDERS, 1994, 9 (05) :493-507

[5] MICROGRAPHIA AS A FOCAL SIGN OF NEUROLOGICAL DISEASE [J].

LEWITT, PA .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1983, 46 (12) :1152-1153

[6] THE MYSTERIOUS MOTOR FUNCTION OF THE BASAL GANGLIA - THE ROBERT WARTENBERG LECTURE [J].

MARSDEN, CD .

NEUROLOGY, 1982, 32 (05) :514-539

[7] MICROGRAPHIA SECONDARY TO LENTICULAR HEMATOMA [J].

MARTINEZVILA, E ;

ARTIEDA, J ;

OBESO, JA .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1988, 51 (10) :1353-1353

[8]

Mozley PD, 1996, J NUCL MED, V37, P1965

[9] Upper-limb dystonia secondary to a midbrain hemorrhage [J].

Munoz, JE ;

Tolosa, E ;

Saiz, A ;

Vila, N ;

Marti, MJ ;

Blesa, R .

MOVEMENT DISORDERS, 1996, 11 (01) :96-99

[10] MICROGRAPHIA WITH COGNITIVE DYSFUNCTION - MINIMAL SEQUELAE OF A PUTAMINAL INFARCT [J].

PULLICINO, P ;

LICHTER, D ;

BENEDICT, R .

MOVEMENT DISORDERS, 1994, 9 (03) :371-373

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