Constituents of holothuroidea, 14.: isolation and structure of new glucocerebroside molecular species from the sea cucumber Stichopus japonicus

被引：26

作者：

Kisa, F ^{[1
]}

Yamada, K ^{[1
]}

Kaneko, M ^{[1
]}

Inagaki, M ^{[1
]}

Higuchi, R ^{[1
]}

机构：

[1] Kyushu Univ, Fac Pharmaceut Sci, Higashi Ku, Fukuoka 8128582, Japan

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2005年 / 53卷 / 04期

关键词：

glycosphingolipid; glucocerebroside; sea cucumber; Stichopus japonicus;

D O I：

10.1248/cpb.53.382

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Five glucocerebroside molecular species, SX-1-SX-5, have been isolated from the less polar lipid fraction of a chloroform/methanol extract of the sea cucumber Stich opus japonicus. The structures of these glucocerebroside molecular species were determined on the basis of chemical and spectroscopic evidence. SX-1, SJC-2, and SJC-3 are typical sphingosine- and phytosphingosine-type glucocerebroside molecular species with nonhydroxylated and hydroxylated fatty acyl moieties. SJC-4 and SJC-5 are also sphingosine-type glucocerebroside molecular species with hydroxylated fatty acyl moieties, although they are new glucocerebroside molecular species with unique sphingosine bases.

引用

页码：382 / 386

页数：5

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