Plant Polyphenols: Natural and Potent UV-Protective Agents for the Prevention and Treatment of Skin Disorders

被引：10
|
作者：
Farjadmand, Fatemeh [1 ]
Karimpour-Razkenari, Elahe [2 ]
Nabavi, Seyed Mohammad [3 ]
Ardekani, Mohammad Reza Shams [1 ,4 ]
Saeedi, Mina [1 ,5 ]
机构：
[1] Univ Tehran Med Sci, Persian Med & Pharm Res Ctr, Tehran, Iran
[2] Mazandaran Univ Med Sci, Dept Clin Pharm, Fac Pharm, Sari, Mazandaran, Iran
[3] Baqiyatallah Univ Med Sci, Appl Biotechnol Res Ctr, Tehran, Iran
[4] Univ Tehran Med Sci, Dept Pharmacognosy, Fac Pharm, Tehran, Iran
[5] Univ Tehran Med Sci, Med Plants Res Ctr, Fac Pharm, POB 14155-6451, Tehran 14176, Iran
来源：
MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2021年 / 21卷 / 05期
关键词：
Phenolic compounds; polyhydroxy phenols; polyphenols; skin cancer; skin protection; sunscreen; UV protection; GREEN TEA POLYPHENOLS; IN-VITRO ANTIOXIDANT; ULTRAVIOLET-RADIATION; DNA-DAMAGE; EPIGALLOCATECHIN-3-GALLATE EGCG; CANCER CHEMOPREVENTION; MOLECULAR-MECHANISMS; OXIDATIVE STRESS; RED WINE; PHOTOPROTECTION;
D O I：
10.2174/1389557520666201109121246
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Nowadays, destructive and immunosuppressive effects from long-term exposure to UV radiation have been fully investigated and documented in the literature. UV radiation is known as the main cause of skin aging and carcinogenesis. Hence, skin protection against anti-oxidative and immu-nosuppressive processes is highly in demand. Now, plant polyphenols have been found as a versatile and natural tool for the prevention and treatment of various skin diseases. The presence of a large number of hydroxyl groups in the cyclic structure of polyphenols has induced valuable biological ac-tivities. Among them, their UV protective activity has attracted lots of attention due to promising effi-cacy and simple instruction to use.
引用
收藏
页码：576 / 585
页数：10
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