The two faces of the 'good' cholesterol

被引：21

作者：

Ansell, Benjamin J.

机构：

[1] Univ Calif Los Angeles, Dept Med, Div Cardiol, Atherosclerosis Res Unit, Los Angeles, CA 90024 USA

[2] Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA USA

来源：

CLEVELAND CLINIC JOURNAL OF MEDICINE | 2007年 / 74卷 / 10期

关键词：

D O I：

10.3949/ccjm.74.10.697

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Although a low level of high-density lipoprotein (HDL) cholesterol is a useful clinical predictor of coronary heart disease, raising the HDL cholesterol level does not necessarily lower this risk. Part of the explanation for this paradox may be that, under certain conditions, HDL either can be less functional as an antioxidant or can even enhance the oxidation and inflammation associated with atherosclerotic plaque. Thus, the functional properties of HDL-not simply the level-may need to be considered and optimized.

引用

页码：697 / +

页数：7

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