Stem cell therapy for nerve injury

被引：57
作者：
Fathi, Sara Sayad [1 ]
Zaminy, Arash [1 ,2 ]
机构：
[1] Guilan Univ Med Sci, Sch Med, Dept Anat Sci, Rasht Tehran Highway, Rasht 4199613769, Iran
[2] Guilan Univ Med Sci, Sch Med, Neurosci Res Ctr, Rasht 4199613769, Iran
来源：
WORLD JOURNAL OF STEM CELLS | 2017年 / 9卷 / 09期
关键词：
Cell-based therapies; Peripheral nerve injury; Stem cells; Mesenchymal stem cells; Bone marrow mesenchymal stem cells; Adipose-derived mesenchymal stem cells; Umbilical cord mesenchymal stem cells; MARROW STROMAL CELLS; HEPATOCYTE GROWTH-FACTOR; PLATELET-RICH PLASMA; PERIPHERAL-NERVE; SCIATIC-NERVE; SCHWANN-CELLS; FUNCTIONAL RECOVERY; NEURITE OUTGROWTH; CLINICAL-APPLICATIONS; NEUROTROPHIC FACTORS;
D O I：
10.4252/wjsc.v9.i9.144
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Peripheral nerve injury has remained a substantial clinical complication with no satisfactory treatment options. Despite the great development in the field of microsurgery, some severe types of neural injuries cannot be treated without causing tension to the injured nerve. Thus current studies have focused on the new approaches for the treatment of peripheral nerve injuries. Stem cells with the ability to differentiate into a variety of cell types have brought a new perspective to this matter. In this review, we will discuss the use of three main sources of mesenchymal stem cells in the treatment of peripheral nerve injuries.
引用
收藏
页码：144 / 151
页数：8
相关论文
共 111 条
  • [91] TERENGHI G, 1995, HISTOL HISTOPATHOL, V10, P709
  • [92] Thompson DM, 2004, ANN BIOMED ENG, V32, P1120
  • [93] Stem-cell plasticity and therapy for injuries of the peripheral nervous system
    Tohill, M
    Terenghi, G
    [J]. BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, 2004, 40 : 17 - 24
  • [94] Rat bone marrow mesenchymal stem cells express glial markers and stimulate nerve regeneration
    Tohill, M
    Mantovani, C
    Wiberg, M
    Terenghi, G
    [J]. NEUROSCIENCE LETTERS, 2004, 362 (03) : 200 - 203
  • [95] GLIAL DIFFERENTIATION OF HUMAN ADIPOSE-DERIVED STEM CELLS: IMPLICATIONS FOR CELL-BASED TRANSPLANTATION THERAPY
    Tomita, K.
    Madura, T.
    Sakai, Y.
    Yano, K.
    Terenghi, G.
    Hosokawa, K.
    [J]. NEUROSCIENCE, 2013, 236 : 55 - 65
  • [96] RATE OF RECOVERY IN MOTOR AND SENSORY FIBRES OF RADIAL NERVE - CLINICAL AND ELECTROPHYSIOLOGICAL ASPECTS
    TROJABORG, W
    [J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1970, 33 (05) : 625 - +
  • [97] Long-term observation of auto-cell transplantation in non-human primate reveals safety and efficiency of bone marrow stromal cell-derived Schwann cells in peripheral nerve regeneration
    Wakao, Shohei
    Hayashi, Takuya
    Kitada, Masaaki
    Kohama, Misaki
    Matsue, Dai
    Teramoto, Noboru
    Ose, Takayuki
    Itokazu, Yutaka
    Koshino, Kazuhiro
    Watabe, Hiroshi
    Iida, Hidehiro
    Takamoto, Tomoaki
    Tabata, Yasuhiko
    Dezawa, Mari
    [J]. EXPERIMENTAL NEUROLOGY, 2010, 223 (02) : 537 - 547
  • [98] SUPPLEMENTATION OF ACELLULAR NERVE GRAFTS WITH SKIN DERIVED PRECURSOR CELLS PROMOTES PERIPHERAL NERVE REGENERATION
    Walsh, S.
    Biernaskie, J.
    Kemp, S. W. P.
    Midha, R.
    [J]. NEUROSCIENCE, 2009, 164 (03) : 1097 - 1107
  • [99] Practical considerations concerning the use of stem cells for peripheral nerve repair
    Walsh, Sarah
    Midha, Rajiv
    [J]. NEUROSURGICAL FOCUS, 2009, 26 (02) : 1 - 8
  • [100] Bone marrow mesenchymal stem cells promote cell proliferation and neurotrophic function of Schwann cells in vitro and in vivo
    Wang, Jie
    Ding, Fei
    Gu, Yun
    Liu, Jie
    Gu, Xiaosong
    [J]. BRAIN RESEARCH, 2009, 1262 : 7 - 15
3456789101112