Stem cell therapy for nerve injury

被引:57
作者
Fathi, Sara Sayad [1 ]
Zaminy, Arash [1 ,2 ]
机构
[1] Guilan Univ Med Sci, Sch Med, Dept Anat Sci, Rasht Tehran Highway, Rasht 4199613769, Iran
[2] Guilan Univ Med Sci, Sch Med, Neurosci Res Ctr, Rasht 4199613769, Iran
来源
WORLD JOURNAL OF STEM CELLS | 2017年 / 9卷 / 09期
关键词
Cell-based therapies; Peripheral nerve injury; Stem cells; Mesenchymal stem cells; Bone marrow mesenchymal stem cells; Adipose-derived mesenchymal stem cells; Umbilical cord mesenchymal stem cells; MARROW STROMAL CELLS; HEPATOCYTE GROWTH-FACTOR; PLATELET-RICH PLASMA; PERIPHERAL-NERVE; SCIATIC-NERVE; SCHWANN-CELLS; FUNCTIONAL RECOVERY; NEURITE OUTGROWTH; CLINICAL-APPLICATIONS; NEUROTROPHIC FACTORS;
D O I
10.4252/wjsc.v9.i9.144
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Peripheral nerve injury has remained a substantial clinical complication with no satisfactory treatment options. Despite the great development in the field of microsurgery, some severe types of neural injuries cannot be treated without causing tension to the injured nerve. Thus current studies have focused on the new approaches for the treatment of peripheral nerve injuries. Stem cells with the ability to differentiate into a variety of cell types have brought a new perspective to this matter. In this review, we will discuss the use of three main sources of mesenchymal stem cells in the treatment of peripheral nerve injuries.
引用
收藏
页码:144 / 151
页数:8
相关论文
共 111 条
  • [1] Human Hair Follicle Pluripotent Stem (hfPS) Cells Promote Regeneration of Peripheral-Nerve Injury: An Advantageous Alternative to ES and iPS Cells
    Amoh, Yasuyuki
    Kanoh, Maho
    Niiyama, Shiro
    Hamada, Yuko
    Kawahara, Katsumasa
    Sato, Yuichi
    Hoffman, Robert M.
    Katsuoka, Kensei
    [J]. JOURNAL OF CELLULAR BIOCHEMISTRY, 2009, 107 (05) : 1016 - 1020
  • [2] Peripheral nervous system involvement in patients with cancer
    Antoine, Jean-Christophe
    Camdessanche, Jean-Philippe
    [J]. LANCET NEUROLOGY, 2007, 6 (01) : 75 - 86
  • [3] Collagen nerve guides for surgical repair of brachial plexus birth injury
    Ashley, William W., Jr.
    Weatherly, Trisha
    Park, Tae Sung
    [J]. JOURNAL OF NEUROSURGERY, 2006, 105 (06) : 452 - 456
  • [4] Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats - similarities to astrocyte grafts
    Azizi, SA
    Stokes, D
    Augelli, BJ
    DiGirolamo, C
    Prockop, DJ
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (07) : 3908 - 3913
  • [5] Updates on stem cells and their applications in regenerative medicine
    Bajada, Stefan
    Mazakova, Irena
    Richardson, James B.
    Ashammakhi, Nureddin
    [J]. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 2008, 2 (04) : 169 - 183
  • [6] Mesenchymal stem cells: clinical applications and biological characterization
    Barry, FP
    Murphy, JM
    [J]. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2004, 36 (04) : 568 - 584
  • [7] Nerve repair by means of tubulization: Literature review and personal clinical experience comparing biological and synthetic conduits for sensory nerve repair
    Battiston, B
    Geuna, S
    Ferrero, M
    Tos, P
    [J]. MICROSURGERY, 2005, 25 (04) : 258 - 267
  • [8] Falls and peripheral nerve injuries: an age-dependent relationship
    Bekelis, Kimon
    Missios, Symeon
    Spinner, Robert J.
    [J]. JOURNAL OF NEUROSURGERY, 2015, 123 (05) : 1223 - 1229
  • [9] Collagen Conduit Versus Microsurgical Neurorrhaphy: 2-Year Follow-Up of a Prospective, Blinded Clinical and Electrophysiological Multicenter Randomized, Controlled Trial
    Boeckstyns, Michel E. H.
    Sorensen, Allan Ibsen
    Vineta, Joaquin Pores
    Rosen, Birgitta
    Navarro, Xavier
    Archibald, Simon J.
    Valss-Sole, Josep
    Moldovan, Mihai
    Krarup, Christian
    [J]. JOURNAL OF HAND SURGERY-AMERICAN VOLUME, 2013, 38A (12): : 2405 - 2411
  • [10] Neurotrophic factors and their receptors in axonal regeneration and functional recovery after peripheral nerve injury
    Boyd, JG
    Gordon, T
    [J]. MOLECULAR NEUROBIOLOGY, 2003, 27 (03) : 277 - 323