Regulatory RNA in Bacterial Pathogens

被引：278
作者：
Papenfort, Kai [1 ,2 ]
Vogel, Joerg [1 ,2 ]
机构：
[1] Max Planck Inst Infect Biol, RNA Biol Grp, D-10117 Berlin, Germany
[2] Univ Wurzburg, Inst Mol Infect Biol, D-97080 Wurzburg, Germany
来源：
CELL HOST & MICROBE | 2010年 / 8卷 / 01期
关键词：
ENTERICA SEROVAR TYPHIMURIUM; SMALL NONCODING RNAS; STAPHYLOCOCCUS-AUREUS REVEALS; CHOLERAE SOLUBLE-RNA; MESSENGER-RNA; PSEUDOMONAS-AERUGINOSA; VIBRIO-CHOLERAE; 6S RNA; LISTERIA-MONOCYTOGENES; ESCHERICHIA-COLI;
D O I：
10.1016/j.chom.2010.06.008
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Bacteria constitute a large and diverse class of infectious agents, causing devastating diseases in humans, animals, and plants. Our understanding of gene expression control, which forms the basis for successful prevention and treatment strategies, has until recently neglected the many roles that regulatory RNAs might have in bacteria. In recent years, several such regulators have been found to facilitate host-microbe interactions and act as key switches between saprophytic and pathogenic lifestyles. This review covers the versatile regulatory RNA mechanisms employed by bacterial pathogens and highlights the dynamic interplay between riboregulation and virulence factor expression.
引用
收藏
页码：116 / 127
页数：12
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