In-situ growth of gold nanoparticles on a 3D-network consisting of a MoS2/rGO nanocomposite for simultaneous voltammetric determination of ascorbic acid, dopamine and uric acid

A glassy carbon electrode was modified with a 3D-networked nanostructure composed of MoS2, reduced graphene oxide and gold nanoparticles (3D-MoS2/rGO/Au). The composites were prepared through in-situ growth of gold nanoparticles on 3D-MoS2/rGO nanosheets via a hydrothermal method. The morphology and electrochemical features of the composite were investigated. The 3D-MoS2/rGO/Au sensor exhibits excellent electrocatalytic activity for simultaneous detection of ascorbic acid (AA), dopamine (DA) and uric acid (UA). The oxidation potentials are well separated at around -0.05V for AA, 0.06V for DA and 0.2V for UA, respectively. The detection limits for individual detection and simultaneous detection (S/N=3) are 0.93M and 1.46M for AA, 0.11M and 0.15M for DA, and 0.74M and 0.29M for UA. The method was applied to the quantitative analysis of AA, DA, and UA in spiked serum samples with satisfying results.