Inflammatory myofibroblastic tumor in colon

被引：28

作者：

Kim, Eun Young ^{[1
]}

Lee, In Kyu ^{[1
]}

Lee, Yoon Suk ^{[1
]}

Yang, Naery ^{[1
]}

Chung, Dong Jin ^{[2
]}

Yim, Kwang-il ^{[3
]}

Kim, Jin Il ^{[4
]}

Oh, Seung Taek ^{[1
]}

机构：

[1] Catholic Univ Korea Sch Med, Dept Surg, Seoul 150713, South Korea

[2] Catholic Univ Korea Sch Med, Dept Radiol, Seoul 150713, South Korea

[3] Catholic Univ Korea Sch Med, Dept Hosp Pathol, Seoul 150713, South Korea

[4] Catholic Univ Korea Sch Med, Dept Internal Med, Seoul 150713, South Korea

来源：

JOURNAL OF THE KOREAN SURGICAL SOCIETY | 2012年 / 82卷 / 01期

关键词：

Inflammatory myofibroblastic tumor; Colon; LYMPHOMA KINASE ALK; IMMUNOHISTOCHEMICAL FEATURES; EXPRESSION;

D O I：

10.4174/jkss.2012.82.1.45

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Inflammatory myofibroblastic tumor (IMT) is an uncommon mesenchymal solid tumor commonly documented in children and young adults. Here, we report a case of IMT in colon confirmed pathologically after laparoscopic anterior resection. A 35-year-old man presented with anal bleeding after defecation for 2 weeks. Colonoscopy demonstrated a mass with shallow ulceration in the central area and irregular margin accompanied by intact mucosa in the descending colon. Computer tomography showed a well-demarcated and homogenous solitary mass in the descending colon. We performed laparoscopic anterior resection. This case was diagnosed as IMT after microscopic examination. The tumor was composed of a proliferation of spindle-shaped cells arranged in the hyaline material with chronic inflammatory cells, composed mainly of plasma cells and lymphocytes. Immunohistochemically, tumor cells were positive for smooth muscle actin, and vimentin, and negative for desmin, CD117 (c-kit), anaplastic lymphoma kinase-1.

引用

页码：45 / 49

页数：5

共 10 条

[1] Pediatric inflammatory myofibroblastic tumor: Anaplastic lymphoma kinase (ALK) expression and prognosis [J].