Unusual rearrangement of the α-globin gene cluster containing both the -α3.7 and αααanti-4.2 crossover junctions:: Clinical diagnostic implications and possible mechanisms

被引：36
作者：
Wang, W
Chan, AYY
Chan, LC
Ma, ESK
Chong, SS
机构：
[1] Department of Pediatrics, National University of Singapore, Singapore
[2] Department of Pathology, University of Hong Kong, Queen Mary Hospital, Hong Kong
[3] Molecular Diagnosis Center, National University Hospital, Singapore
[4] Department of Pediatrics, National University of Singapore, National University Hospital, Singapore 119074
来源：
CLINICAL CHEMISTRY | 2005年 / 51卷 / 11期
关键词：
D O I：
10.1373/clinchem.2005.054189
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
[No abstract available]
引用
收藏
页码：2167 / 2170
页数：4
相关论文
共 10 条
  • [1] HEMOGLOBIN PARCHMAN - DOUBLE CROSSOVER WITHIN A SINGLE HUMAN-GENE
    ADAMS, JG
    MORRISON, WT
    STEINBERG, MH
    [J]. SCIENCE, 1982, 218 (4569) : 291 - 293
  • [2] ALPHA-ALPHA-ALPHA-ALPHA-ANTI-3.7 TYPE-II - A NEW ALPHA-GLOBIN GENE REARRANGEMENT SUGGESTING THAT THE ALPHA-GLOBIN GENE DUPLICATION COULD BE CAUSED BY INTRACHROMOSOMAL RECOMBINATION
    DEANGIOLETTI, M
    LACERRA, G
    CASTALDO, C
    CUTOLO, R
    DEBONIS, C
    BUONANNO, G
    CARESTIA, C
    [J]. HUMAN GENETICS, 1992, 89 (01) : 37 - 41
  • [3] DETECTION OF A NEW HYBRID ALPHA-2 GLOBIN GENE AMONG AMERICAN BLACKS
    GU, YC
    NAKATSUJI, T
    HUISMAN, THJ
    [J]. HUMAN GENETICS, 1988, 79 (01) : 68 - 72
  • [4] 2 DIFFERENT QUADRUPLICATED ALPHA-GLOBIN GENE ARRANGEMENTS
    GU, YC
    LANDMAN, H
    HUISMAN, THJ
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 1987, 66 (02) : 245 - 250
  • [5] Ma ESK, 2000, HAEMATOLOGICA, V85, P991
  • [6] Ma ESK, 2002, HAEMATOLOGICA, V87, P443
  • [7] METZENBERG AB, 1991, GENETICS, V128, P143
  • [8] A rapid and reliable 7-deletion multiplex polymerase chain reaction assay for α-thalassemia
    Tan, ASC
    Quah, TC
    Low, PS
    Chong, SS
    [J]. BLOOD, 2001, 98 (01) : 250 - 251
  • [9] Single-tube multiplex-PCR screen for anti-3.7 and anti-4.2 α-globin gene triplications
    Wang, W
    Ma, ESK
    Chan, AYY
    Prior, J
    Erber, WN
    Chan, LC
    Chui, DHK
    Chong, SS
    [J]. CLINICAL CHEMISTRY, 2003, 49 (10) : 1679 - 1682
  • [10] WEATHERALL DJ, 2001, THALASSAEMIA SYNDROM, P136
1