The Korean Severe Asthma Registry (KoSAR): real world research in severe asthma

被引：20

作者：

Kim, Sang-Heon ^{[1
]}

Lee, Hyun ^{[1
]}

Park, So-Young ^{[2
]}

Park, So Young ^{[3
]}

Song, Woo-Jung ^{[4
]}

Kim, Joo-Hee ^{[5
]}

Park, Heung-Woo ^{[6
]}

Cho, You Sook ^{[4
]}

Yoon, Ho Joo ^{[1
]}

机构：

[1] Hanyang Univ, Dept Internal Med, Coll Med, Seoul, South Korea

[2] Chung Ang Univ, Dept Internal Med, Div Pulm Allergy & Crit Care Med, Coll Med, Seoul, South Korea

[3] Eulji Univ, Eulji Gen Hosp, Dept Internal Med, Sch Med, Seoul, South Korea

[4] Univ Ulsan, Asan Med Ctr, Dept Allergy & Clin Immunol, Coll Med, Seoul, South Korea

[5] Hallym Univ, Dept Internal Med, Sacred Heart Hosp, Anyang, South Korea

[6] Seoul Natl Univ, Dept Internal Med, Coll Med, Seoul, South Korea

来源：

KOREAN JOURNAL OF INTERNAL MEDICINE | 2022年 / 37卷 / 02期

关键词：

Severe asthma; Registries; Biological products; Real world; SEVERE ALLERGIC-ASTHMA; REFRACTORY ASTHMA; PREVALENCE; OMALIZUMAB; MANAGEMENT; CARE; HETEROGENEITY; BIOLOGICALS; POPULATION; DEFINITION;

D O I：

10.3904/kjim.2021.403

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Severe asthma constitutes a serious health burden with significant morbidity and socioeconomic costs. The development and introduction of new biologics targeting type 2 inflammation changed the paradigm for management of severe asthma and initiated a biological era. These changes impose a challenge to clinicians in managing difficult-to-treat and severe asthma. To understand the characteristics and heterogeneity of severe asthma and to develop a better strategy to manage it, the Korean Academy of Asthma, Allergy and Clinical Immunology, Working Group on Severe Asthma, has organized the Korean Severe Asthma Registry (KoSAR). In this review, we describe the challenges of severe asthma management regarding diagnosis, disease burden, heterogeneity, guidelines, and organization of severe asthma clinics. This review also examines the current global activities of national and regional registries and study groups. In addition, we present the KoSAR vision and organization and describe the findings of KoSAR in comparison with those of other countries.

引用

页码：249 / 260

页数：12

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