What comes first, misshape or dysfunction? The view from metabolic excess

被引：45
作者：
Galloway, Chad A. [1 ,3 ]
Yoon, Yisang [1 ,2 ,3 ]
机构：
[1] Univ Rochester, Sch Med & Dent, Dept Anesthesiol, Rochester, NY 14642 USA
[2] Univ Rochester, Sch Med & Dent, Dept Pharmacol & Physiol, Rochester, NY 14642 USA
[3] Univ Rochester, Sch Med & Dent, Mitochondrial Res & Innovat Grp, Rochester, NY 14642 USA
来源：
JOURNAL OF GENERAL PHYSIOLOGY | 2012年 / 139卷 / 06期
关键词：
DYNAMIN-RELATED PROTEIN; REGULATES MITOCHONDRIAL MORPHOLOGY; HUMAN NONALCOHOLIC STEATOHEPATITIS; DOMINANT OPTIC ATROPHY; CYTOCHROME-C RELEASE; DIABETIC HUMAN HEART; CELL-DEATH; ENDOPLASMIC-RETICULUM; CALCIUM-IONS; MITOFUSIN;
D O I：
10.1085/jgp.201210771
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
[No abstract available]
引用
收藏
页码：455 / 463
页数：9
相关论文
共 67 条
[1]   OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28 [J].
Alexander, C ;
Votruba, M ;
Pesch, UEA ;
Thiselton, DL ;
Mayer, S ;
Moore, A ;
Rodriguez, M ;
Kellner, U ;
Leo-Kottler, B ;
Auburger, G ;
Bhattacharya, SS ;
Wissinger, B .
NATURE GENETICS, 2000, 26 (02) :211-215
[2]   Increased propensity for cell death in diabetic human heart is mediated by mitochondrial-dependent pathways [J].
Anderson, Ethan J. ;
Rodriguez, Evelio ;
Anderson, Curtis A. ;
Thayne, Kathleen ;
Chitwood, W. Randolph ;
Kypson, Alan P. .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2011, 300 (01) :H118-H124
[3]   Substrate-Specific Derangements in Mitochondrial Metabolism and Redox Balance in the Atrium of the Type 2 Diabetic Human Heart [J].
Anderson, Ethan J. ;
Kypson, Alan P. ;
Rodriguez, Evelio ;
Anderson, Curtis A. ;
Lehr, Eric J. ;
Neufer, P. Darrell .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 54 (20) :1891-1898
[4]   Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism -: A novel regulatory mechanism altered in obesity [J].
Bach, D ;
Pich, S ;
Soriano, FX ;
Vega, N ;
Baumgartner, B ;
Oriola, J ;
Daugaard, JR ;
Lloberas, J ;
Camps, M ;
Zierath, JR ;
Rabasa-Lhoret, R ;
Wallberg-Henriksson, H ;
Laville, M ;
Palacín, M ;
Vidal, H ;
Rivera, F ;
Brand, M ;
Zorzano, A .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (19) :17190-17197
[5]   Mitochondrial bioenergetics and structural network organization [J].
Benard, Giovanni ;
Bellance, Nadege ;
James, Dominic ;
Parrone, Philippe ;
Fernandez, Helder ;
Letellier, Thierry ;
Rossignol, Rodrigue .
JOURNAL OF CELL SCIENCE, 2007, 120 (05) :838-848
[6]   Calcium, ATP, and ROS: a mitochondrial love-hate triangle [J].
Brookes, PS ;
Yoon, YS ;
Robotham, JL ;
Anders, MW ;
Sheu, SS .
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2004, 287 (04) :C817-C833
[7]   Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins [J].
Brooks, Craig ;
Wei, Qingqing ;
Feng, Leping ;
Dong, Guie ;
Tao, Yanmei ;
Mei, Lin ;
Xie, Zi-Jian ;
Dong, Zheng .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (28) :11649-11654
[8]   Mitochondrial abnormalities in non-alcoholic steatohepatitis [J].
Caldwell, SH ;
Swerdlow, RH ;
Khan, EM ;
Iezzoni, JC ;
Hespenheide, EE ;
Parks, JK ;
Parker, WD .
JOURNAL OF HEPATOLOGY, 1999, 31 (03) :430-434
[9]   Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria [J].
Cereghetti, G. M. ;
Stangherlin, A. ;
de Brito, O. Martins ;
Chang, C. R. ;
Blackstone, C. ;
Bernardi, P. ;
Scorrano, L. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (41) :15803-15808
[10]   Disruption of fusion results in mitochondrial heterogeneity and dysfunction [J].
Chen, HC ;
Chomyn, A ;
Chan, DC .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (28) :26185-26192
1234567