Yellow fever vaccination during treatment with infliximab in a patient with ulcerative colitis: A case report

被引：6

作者：

Rueddel, J. ^{[1
]}

Schleenvoigt, B. T. ^{[2
]}

Schueler, E. ^{[3
]}

Schmidt, C. ^{[1
,4
]}

Pletz, M. W. ^{[2
,4
]}

Stallmach, A. ^{[1
]}

机构：

[1] Jena Univ Hosp, Dept Internal Med 4, Dept Gastroenterol Hepatol & Infect Dis, Erlanger Allee 101, D-07740 Jena, Germany

[2] Jena Univ Hosp, Ctr Infect Dis & Infect Control, Jena, Germany

[3] City Erfurt, Hlth Off, Erfurt, Germany

[4] Jena Univ Hosp, Ctr Sepsis Control & Care CSCC, Jena, Germany

来源：

ZEITSCHRIFT FUR GASTROENTEROLOGIE | 2016年 / 54卷 / 09期

关键词：

inflammatory bowel disease; yellow fever vaccine; infliximab; ulcerative colitis; INFLAMMATORY-BOWEL-DISEASE; EVIDENCE-BASED CONSENSUS; OPPORTUNISTIC INFECTIONS; PREVENTION; DIAGNOSIS; IMMUNOGENICITY; MANAGEMENT; GUIDELINE; THERAPIES; VACCINES;

D O I：

10.1055/s-0042-109871

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

We report the case of a 59-year-old patient who accidentally underwent live vaccination against yellow fever during continuous treatment with the TNF-alpha-antibody (AB) infliximab for ulcerative colitis. The clinical course showed fever of short duration and elevation of liver enzymes without further clinical complications. Yellow fever viremia was not detectable and protective antibodies were developed. A primary vaccination against yellow fever under infliximab has not been reported in the literature before, although vaccination is an important topic in IBD. Live vaccinations, like Stamaril (R) against yellow fever, are contraindicated during TNF-alpha-AB treatment. Treatment regimens containing TNF-alpha-AB are of growing importance, not only in gastroenterology, but also in rheumatology and dermatology. We discuss this topic by presenting our case and reviewing the current literature.

引用

页码：1081 / 1084

页数：4

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