Laboratory Diagnostics for Hepatitis C Virus Infection

被引：112

作者：

Kamili, Saleem ^{[1
]}

Drobeniuc, Jan ^{[1
]}

Araujo, Aufra C. ^{[1
]}

Hayden, Tonya M. ^{[1
]}

机构：

[1] Ctr Dis Control & Prevent, Natl Ctr HIV Hepatitis STD TB Prevent, Div Viral Hepatitis, Atlanta, GA 30333 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2012年 / 55卷

关键词：

MEDIATED ISOTHERMAL AMPLIFICATION; HCV CORE ANTIGEN; RNA APTAMERS; NON-A; ANTIBODY; ASSAYS; AVIDITY; SYSTEM; IGG;

D O I：

10.1093/cid/cis368

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Identification of prevalent infection by hepatitis C virus (HCV) is based serologically on detecting anti-HCV immunoglobulin G, using immunoassays, immunoblot assays, and, more recently, immunochromatography-based rapid tests. None discriminate between active and resolved HCV infection. Tests for detecting HCV RNA identify active HCV infection but are costly. Serologic assays for HCV antigens have been developed and show potential for diagnosis of active HCV infection, and their performance characteristics are undergoing evaluation. The diagnosis of acute HCV infection without the demonstration of seroconversion remains elusive.

引用

收藏

页码：S43 / S48

页数：6

相关论文

共 44 条

[1]

Al Olaby RR, 2011, EXPERT REV MOL DIAGN, V11, P53, DOI [10.1586/erm.10.101, 10.1586/ERM.10.101]

[2] NEW KIT ON THE BLOCK - EVALUATION OF 2ND-GENERATION ASSAYS FOR DETECTION OF ANTIBODY TO THE HEPATITIS-C VIRUS [J].

ALTER, HJ .

HEPATOLOGY, 1992, 15 (02) :350-351

[3]

[Anonymous], 2003, MMWR MORB MORTAL WKL

[4] Distinguishing Acute from Chronic Hepatitis C Virus (HCV) Infection Based on Antibody Reactivities to Specific HCV Structural and Nonstructural Proteins [J].

Araujo, Aufra C. ;

Astrakhantseva, Irina V. ;

Fields, Howard A. ;

Kamili, Saleem .

JOURNAL OF CLINICAL MICROBIOLOGY, 2011, 49 (01) :54-57

[5] Nanodiagnostics: A new frontier for clinical laboratory medicine [J].

Azzazy, Hassan M. E. ;

Mansour, Mai M. H. ;

Kazmierczak, Steven C. .

CLINICAL CHEMISTRY, 2006, 52 (07) :1238-1246

[6] INCIDENCE OF NON-A, NON-B HEPATITIS AFTER SCREENING BLOOD-DONORS FOR ANTIBODIES TO HEPATITIS-C VIRUS AND SURROGATE MARKERS [J].

BARRERA, JM ;

BRUGUERA, M ;

ERCILLA, G ;

SANCHEZTAPIAS, JM ;

GIL, MP ;

GIL, C ;

COSTA, J ;

GELABERT, A ;

RODES, J ;

CASTILLO, R .

ANNALS OF INTERNAL MEDICINE, 1991, 115 (08) :596-600

[7] IMPROVED DETECTION OF ANTI-HCV IN POSTTRANSFUSION HEPATITIS BY A 3RD-GENERATION ELISA [J].

BARRERA, JM ;

FRANCIS, B ;

ERCILLA, G ;

NELLES, M ;

ACHORD, D ;

DARNER, J ;

LEE, SR .

VOX SANGUINIS, 1995, 68 (01) :15-18

[8] CS-SELEX Generates High-Affinity ssDNA Aptamers as Molecular Probes for Hepatitis C Virus Envelope Glycoprotein E2 [J].

Chen, Fang ;

Hu, Yilan ;

Li, Dongqing ;

Chen, Haidan ;

Zhang, Xiao-Lian .

PLOS ONE, 2009, 4 (12)

[9] Sensitivity and specificity of third-generation hepatitis C virus antibody detection assays: an analysis of the literature [J].

Colin, C ;

Lanoir, D ;

Touzet, S ;

Meyaud-Kraemer, L ;

Bailly, F ;

Trepo, C .

JOURNAL OF VIRAL HEPATITIS, 2001, 8 (02) :87-95

[10] Improvement in the aetiological diagnosis of acute hepatitis C: A diagnostic protocol based on the anti-HCV-IgM titre and IgG Avidity Index [J].

Coppola, Nicola ;

Pisapia, Raffaella ;

Tonziello, Gilda ;

Masiello, Addolorata ;

Martini, Salvatore ;

Pisaturo, Mariantonietta ;

Messina, Vincenzo ;

Sagnelli, Caterina ;

Macera, Margherita ;

Signoriello, Giuseppe ;

Sagnelli, Evangelista .

JOURNAL OF CLINICAL VIROLOGY, 2009, 46 (03) :222-229

← 1 2 3 4 5 →