Transmission of CMV, HTLV-1, and HIV through breastmilk

被引：44
作者：
Prendergast, Andrew J. [1 ,2 ]
Goga, Ameena E. [3 ,4 ]
Waitt, Catriona [5 ,6 ]
Gessain, Antoine [7 ]
Taylor, Graham P. [8 ]
Rollins, Nigel [9 ]
Abrams, Elaine J. [10 ,11 ]
Lyall, E. Hermione [12 ]
Van de Perre, Philippe [13 ]
机构：
[1] Queen Mary Univ London, Blizard Inst, London, England
[2] Zvitambo Inst Maternal & Child Hlth Res, Harare, Zimbabwe
[3] South African Med Res Council, Cape Town, South Africa
[4] Univ Pretoria, Dept Paediat, Hatfield, South Africa
[5] Univ Liverpool, Dept Mol & Clin Pharmacol, Liverpool, Merseyside, England
[6] Makerere Univ, Infect Dis Inst, Coll Hlth Sci, Kampala, Uganda
[7] Inst Pasteur, EPVO Unit, Paris, France
[8] Imperial Coll London, Sect Virol, London, England
[9] WHO, Dept Maternal Newborn Child & Adolescent Hlth, Geneva, Switzerland
[10] Columbia Univ, ICAP Columbia, Mailman Sch Publ Hlth, New York, NY USA
[11] Columbia Univ, Vagelos Coll Phys & Surg, New York, NY USA
[12] Imperial Coll Healthcare NHS Trust, Dept Paediat, London, England
[13] Univ Montpellier, CHU Montpellier, Pathogenesis & Control Chron Infect, INSERM,Etab Francais Sang, Montpellier, France
来源：
LANCET CHILD & ADOLESCENT HEALTH | 2019年 / 3卷 / 04期
关键词：
TO-CHILD TRANSMISSION; ACTIVE ANTIRETROVIRAL THERAPY; POSTNATAL CYTOMEGALOVIRUS-INFECTION; SUB-SAHARAN AFRICA; PRETERM INFANTS; CELL-LEUKEMIA/LYMPHOMA; DRUG-RESISTANCE; VIRUS; MOTHER; WOMEN;
D O I：
10.1016/S2352-4642(19)30024-0
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Breastfeeding is a crucial child survival intervention. However, the potential for transmission of viral infections from mother to child presents the dilemma of how best to interpret the benefits and risks of breastfeeding in different settings. In this Review, we compare the transmission dynamics, risk factors, and outcomes of infection with three chronic viruses transmitted through breastmilk: cytomegalovirus, human T-cell lymphotropic virus type 1, and HIV. We provide an overview of intervention approaches and discuss scientific, policy, and programming gaps in the understanding of these major global infections.
引用
收藏
页码：264 / 273
页数：10
相关论文
共 110 条
  • [11] BHIVA, 2020, BRIT HIV ASS GUIDELI
  • [12] Postnatal HIV transmission in breastfed infants of HIV-infected women on ART: a systematic review and meta-analysis
    Bispo, Stephanie
    Chikhungu, Lana
    Rollins, Nigel
    Siegfried, Nandi
    Newell, Marie-Louise
    [J]. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 2017, 20
  • [13] Nonprimary Maternal Cytomegalovirus Infection After Viral Shedding in Infants
    Boucoiran, Isabelle
    Mayer, Bryan T.
    Krantz, Elizabeth M.
    Marchant, Arnaud
    Pati, Sunil
    Boppana, Suresh
    Wald, Anna
    Corey, Larry
    Casper, Corey
    Schiffer, Joshua T.
    Gantt, Soren
    [J]. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2018, 37 (07) : 627 - 631
  • [14] Mucosal immunity: integration between mother and the breast-fed infant
    Brandtzaeg, P
    [J]. VACCINE, 2003, 21 (24) : 3382 - 3388
  • [15] CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract
    Brenchley, JM
    Schacker, TW
    Ruff, LE
    Price, DA
    Taylor, JH
    Beilman, GJ
    Nguyen, PL
    Khoruts, A
    Larson, M
    Haase, AT
    Douek, DC
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2004, 200 (06) : 749 - 759
  • [16] Memory CD4+CCR5+ T cells are abundantly present in the gut of newborn infants to facilitate mother-to-child transmission of HIV-1
    Bunders, Madeleine J.
    van der Loos, Chris M.
    Klarenbeek, Paul L.
    van Hamme, John L.
    Boer, Kees
    Wilde, Jim C. H.
    de Vries, Niek
    van Lier, Rene A. W.
    Kootstra, Neeltje
    Pals, Steven T.
    Kuijpers, Taco W.
    [J]. BLOOD, 2012, 120 (22) : 4383 - 4390
  • [17] Review of cytomegalovirus seroprevalence and demographic characteristics associated with infection
    Cannon, Michael J.
    Schmid, D. Scott
    Hyde, Terri B.
    [J]. REVIEWS IN MEDICAL VIROLOGY, 2010, 20 (04) : 202 - 213
  • [18] Centers for Disease Control (CDC), 1985, MMWR Morb Mortal Wkly Rep, V34, P721
  • [19] Maternal or Infant Antiretroviral Drugs to Reduce HIV-1 Transmission
    Chasela, Charles S.
    Hudgens, Michael G.
    Jamieson, Denise J.
    Kayira, Dumbani
    Hosseinipour, Mina C.
    Kourtis, Athena P.
    Martinson, Francis
    Tegha, Gerald
    Knight, Rodney J.
    Ahmed, Yusuf I.
    Kamwendo, Deborah D.
    Hoffman, Irving F.
    Ellington, Sascha R.
    Kacheche, Zebrone
    Soko, Alice
    Wiener, Jeffrey B.
    Fiscus, Susan A.
    Kazembe, Peter
    Mofolo, Innocent A.
    Chigwenembe, Maggie
    Sichali, Dorothy S.
    van der Horst, Charles M.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2010, 362 (24) : 2271 - 2281
  • [20] Reducing Risk for Mother-to-Infant Transmission of Hepatitis C Virus: A Systematic Review for the US Preventive Services Task Force
    Cottrell, Erika Barth
    Chou, Roger
    Wasson, Ngoc
    Rahman, Basmah
    Guise, Jeanne-Marie
    [J]. ANNALS OF INTERNAL MEDICINE, 2013, 158 (02) : 109 - 113
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