EARLY PHYSICAL AND PSYCHO-EDUCATIONAL REHABILITATION IN PATIENTS WITH CORONARY ARTERY BYPASS GRAFTING: A RANDOMIZED CONTROLLED TRIAL

被引:31
作者
Hojskov, Ida Elisabeth [1 ,2 ]
Moons, Philip [3 ,4 ]
Egerod, Ingrid [5 ]
Olsen, Peter Skov [1 ]
Thygesen, Lau Caspar [6 ]
Hansen, Niels Viggo [7 ]
La Cour, Soren
Bech, Kristina Hindhede [8 ]
Borregaard, Britt [8 ]
Gluud, Christian [9 ]
Winkel, Per [9 ]
Lindschou, Jane [9 ]
Berg, Selina Kikkenborg [1 ]
机构
[1] Univ Copenhagen, Rigshosp, Heart Ctr, Dept Cardiothorac Surg, Blegdamsvej 9, DK-2100 Copenhagen, Denmark
[2] Metropolitan Univ Coll, Fac Hlth & Technol, Dept Nursing, Copenhagen, Denmark
[3] Univ Leuven, Dept Publ Hlth & Primary Care, Leuven, Belgium
[4] Univ Gothenburg, Inst Hlth & Care Sci, Gothenburg, Sweden
[5] Copenhagen Univ Hosp, Rigshosp, Intens Care Unit, Copenhagen, Denmark
[6] Univ Southern Denmark, Natl Inst Publ Hlth, Copenhagen, Denmark
[7] Aarhus Univ, Interacting Minds Ctr, Aarhus, Denmark
[8] Odense Univ Hosp, Dept Cardiothorac & Vasc Surg, Odense, Denmark
[9] Copenhagen Univ Hosp, Rigshosp, Ctr Clin Intervent Res, Copenhagen Trial Unit, Copenhagen, Denmark
关键词
rehabilitation post-CABG; phase; 1; rehabilitation; early rehabilitation; coronary artery bypass grafting; physical exercise; psycho-education; SECONDARY PREVENTION; SURGERY; DEPRESSION; ANXIETY; TESTS;
D O I
10.2340/16501977-2499
中图分类号
R49 [康复医学];
学科分类号
100215 ;
摘要
Objectives: Rehabilitation of patients following coronary artery bypass grafting (CABG) has been widely studied; however, research into early rehabilitation after CABG is sparse. The aim of this trial was to assess the impact of early rehabilitation, compared with usual care in patients following CABG. Design: Randomized controlled trial. Patients: A total of 326 patients treated with CABG. Methods: Patients treated with CABG were randomized 1:1 to 4 weeks of comprehensive early rehabilitation or usual care. The primary outcome was the Six Minute Walk Test (6MWT). Secondary outcomes were mental health and physical activity (Medical Outcome Study Short Form; SF-12); anxiety and depression (Hospital Anxiety and Depression Scale; HADS); physical and emotional scores; sleep (Pittsburgh Sleep Quality Index; PSQI); pain (Orebro Musculoskeletal Screening Questionnaire; OMSQ) and muscle endurance (Sit-To-Stand test). Results: Sixteen patients dropped out. No significant differences between groups in the primary outcome (6MWT) were found after 4 weeks (p = 0.27). For secondary outcomes the odds ratio of HADS-D >= 8 decreased in favour of the experimental intervention (p = 0.04). There was non-adherence to parts of the intervention. Per-protocol analysis showed differences between groups for the 6MWT (p = 0.02) and the Sit-To-Stand test (p = 0.046). Conclusion: In general, the intervention had no effect on the 6MWT, or secondary outcomes, except for depressive symptoms. However, in adherent participants, the intervention had a positive effect for the primary and several secondary outcomes.
引用
收藏
页码:136 / 143
页数:8
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