Increase in power through multivariate analyses

被引:99
作者
Schmitz, S
Cherny, SS
Fulker, DW
机构
[1] Inst Behav Genet, Boulder, CO 80309 USA
[2] Univ Colorado, Hlth Sci Ctr, Dept Psychiat, Denver, CO 80262 USA
[3] Univ London, Inst Psychiat, Genet & Dev Psychiat Res Ctr, London, England
关键词
statistical power; multivariate analyses; power simulations;
D O I
10.1023/A:1021669602220
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Power to detect genetic and environmental influences increases not only with sample size but also with the number of measurements through longitudinal and/or multivariate designs, if those measurements correlate with each other. Power simulations are presented for uni- through quadrivariate cases, with differing genetic and environmental parameters. Even though subject attrition is a problem for most longitudinal studies, the gain in power available may more than make up for this shortcoming in many situations. In terms of planning studies to examine genetic and environmental influences, power calculations should not only consider sample size but number of measurements on particular phenotypes and their intercorrelations.
引用
收藏
页码:357 / 363
页数:7
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