Pediatric Multiple Sclerosis

被引:48
作者
Chitnis, Tanuja [9 ]
Krupp, Lauren [8 ]
Yeh, Ann [4 ]
Rubin, Jennifer [7 ]
Kuntz, Nancy [7 ]
Strober, Jonathan B. [6 ]
Chabas, Dorothee [5 ]
Weinstock-Guttmann, Bianca [3 ,4 ]
Ness, Jayne [1 ]
Rodriguez, Moses [2 ]
Waubant, Emmanuelle [5 ]
机构
[1] Univ Alabama Birmingham, Ctr Pediat Onset Demyelinating Dis, Childrens Hosp Alabama, Birmingham, AL 35233 USA
[2] Mayo Clin, Mayo Clin Pediat Multiple Sclerosis Ctr, Rochester, MN 55905 USA
[3] SUNY Buffalo, Baird Multiple Sclerosis Ctr, Buffalo, NY 14260 USA
[4] SUNY Buffalo, Jacobs Neurol Inst, Pediat Multiple Sclerosis Ctr Excellence, Buffalo, NY 14222 USA
[5] Univ Calif San Francisco, Dept Neurol, UCSF Reg Pediat Multiple Sclerosis Ctr, San Francisco, CA 94143 USA
[6] Univ San Francisco, Pediat Muscular Dystrophy Assoc Clin, Neurol & Pediat UCSF, Div Child Neurol,Dept Neurol, San Francisco, CA 94117 USA
[7] Childrens Mem Hosp, Dept Pediat Neurol, NW Feinberg Sch Med, Chicago, IL 60614 USA
[8] SUNY Stony Brook, Dept Neurol, Natl Pediat Multiple Sclerosis Ctr, Stony Brook, NY 11794 USA
[9] Harvard Univ, Sch Med, Partners Pediat Multiple Sclerosis Ctr, Massachusetts Gen Hosp Children, Boston, MA 02114 USA
关键词
Multiple sclerosis; Children; Pediatric; Treatment; ACUTE DISSEMINATED ENCEPHALOMYELITIS; CENTRAL-NERVOUS-SYSTEM; PLACEBO-CONTROLLED TRIAL; RELEASE ORAL FAMPRIDINE; EPSTEIN-BARR-VIRUS; TERM-FOLLOW-UP; EARLY-ONSET MS; TUMEFACTIVE DEMYELINATION; DIAGNOSTIC-CRITERIA; CHILDHOOD-ONSET;
D O I
10.1016/j.ncl.2011.01.004
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
In the past 5 years, there has been an exponential growth in the knowledge about multiple sclerosis (MS) in children and adolescents. Recent publications have shed light on its diagnosis, pathogenesis, clinical course, and treatment. However, there remain several key areas that require further exploration. This article summarizes the current state of knowledge on pediatric MS and discusses future avenues of investigation.
引用
收藏
页码:481 / +
页数:26
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