Exogenous nitric oxide donors in the series of C-nitro compounds

被引：17
作者：
Granik, V. G. [1 ]
Grigoriev, N. B. [1 ]
机构：
[1] All Russian Res Chem Pharmaceut Inst, Ctr Med Chem, Moscow 119021, Russia
来源：
RUSSIAN CHEMICAL REVIEWS | 2011年 / 80卷 / 02期
关键词：
NO-DONORS; VASODILATING ACTIVITIES; CANCER; DRUGS; ACID; REARRANGEMENT; PATHOPHYSIOLOGY; METRONIDAZOLE; DECOMPOSITION; AZODIOXIDES;
D O I：
10.1070/RC2011v080n02ABEH004135
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The published data on nitrogen (II) oxide donors related to C-nitro compounds are generalized and described systematically. The key classes of these compounds and the possible mechanisms of their transformations under hydrolytic conditions and in living organisms are considered. The attention is focused on C-nitro compounds as potential medicinal agents for treating abroad range of diseases (cardiovascular diseases,tuberculosis,cancer, etc.). The bibliography includes 106 references.
引用
收藏
页码：171 / 186
页数：16
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