Automation of anaesthesia: a review on multivariable control

被引：20
作者：
Chang, Jing Jing [1 ]
Syafiie, S. [1 ]
Kamil, Raja [2 ]
Lim, Thiam Aun [3 ]
机构：
[1] Univ Putra Malaysia, Dept Chem & Environm Engn, Fac Engn, Serdang 43400, Selangor, Malaysia
[2] Univ Putra Malaysia, Dept Elect & Elect Engn, Fac Engn, Serdang 43400, Selangor, Malaysia
[3] Univ Putra Malaysia, Dept Surg, Anaesthesiol Unit, Fac Med & Hlth Sci, Serdang 43400, Selangor, Malaysia
来源：
JOURNAL OF CLINICAL MONITORING AND COMPUTING | 2015年 / 29卷 / 02期
关键词：
Closed-loop anaesthesia; Model uncertainty; Fault-tolerant; MIMO; Depth of anaesthesia; CLOSED-LOOP ANESTHESIA; REMIFENTANIL PHARMACODYNAMIC INTERACTION; TOTAL INTRAVENOUS ANESTHESIA; NEURAL-FUZZY PARADIGMS; BISPECTRAL INDEX; GENERAL-ANESTHESIA; DELIVERY-SYSTEM; DRUG-DELIVERY; PROPOFOL; PHARMACOKINETICS;
D O I：
10.1007/s10877-014-9590-6
中图分类号：
R614 [麻醉学];
学科分类号：
100217 ;
摘要：
Anaesthesia is a multivariable problem where a combination of drugs are used to induce desired hypnotic, analgesia and immobility states. The automation of anaesthesia may improve the safety and cost-effectiveness of anaesthesia. However, the realization of a safe and reliable multivariable closed-loop control of anaesthesia is yet to be achieved due to a manifold of challenges. In this paper, several significant challenges in automation of anaesthesia are discussed, namely model uncertainty, controlled variables, closed-loop application and dependability. The increasingly reliable measurement device, robust and adaptive controller, and better fault tolerance strategy are paving the way for automation of anaesthesia.
引用
收藏
页码：231 / 239
页数：9
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