Fetal Programming: Early-life Modulations that Affect Adult Outcomes

被引:25
作者
Drever, Nathan [1 ]
Saade, George R. [1 ]
Bytautiene, Egle [1 ]
机构
[1] Univ Texas Galveston, Med Branch, Div Maternal Fetal Med, Dept Obstet & Gynecol, Galveston, TX 77555 USA
关键词
Asthma; Fetal programming; Offspring; Epigenetics; LOW-BIRTH-WEIGHT; MATERNAL SMOKING; ALLERGIC SENSITIZATION; LUNG-FUNCTION; IN-UTERO; VITAMIN-E; ASTHMA; EXPOSURE; ASSOCIATION; DISEASE;
D O I
10.1007/s11882-010-0136-9
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Asthma is a common disease, and the number of people diagnosed with it increases every year. Although genetic background and environmental exposures play major roles in the development of asthma, one cannot overlook the developmental origin of adult disease or fetal programming theory. This review examines the social, genetic, and environmental factors that are associated with fetal programming of asthma. We also present recent studies from our laboratory that strengthen these observations. It is our hope that the reader will come away with a current view of fetal programming in asthma.
引用
收藏
页码:453 / 459
页数:7
相关论文
共 59 条
[1]   In utero and postnatal maternal smoking and asthma in adolescence [J].
Alati, R ;
Al Mamun, A ;
O'Callaghan, M ;
Najman, JM ;
Williams, GM .
EPIDEMIOLOGY, 2006, 17 (02) :138-144
[2]   RELATION OF BIRTH-WEIGHT AND CHILDHOOD RESPIRATORY-INFECTION TO ADULT LUNG-FUNCTION AND DEATH FROM CHRONIC OBSTRUCTIVE AIRWAYS DISEASE [J].
BARKER, DJP ;
GODFREY, KM ;
FALL, C ;
OSMOND, C ;
WINTER, PD ;
SHAHEEN, SO .
BRITISH MEDICAL JOURNAL, 1991, 303 (6804) :671-675
[3]  
BARKER DJP, 1986, LANCET, V1, P1077
[4]   Parental allergic status influences the risk of developing allergic sensitization and an asthmatic-like phenotype in canine offspring [J].
Barrett, EG ;
Rudolph, K ;
Bowen, LE ;
Bice, DE .
IMMUNOLOGY, 2003, 110 (04) :493-500
[5]   Is allergic asthma associated with delayed fetal maturation or the persistence of conserved fetal genes? [J].
Bousquet, J ;
Yssel, H ;
Vignola, AM .
ALLERGY, 2000, 55 (12) :1194-1197
[6]   Epigenetic inheritance of fetal genes in allergic asthma [J].
Bousquet, J ;
Jacot, W ;
Yssel, H ;
Vignola, AM ;
Humbert, M .
ALLERGY, 2004, 59 (02) :138-147
[7]   FETAL LUNG HYPOPLASIA ASSOCIATED WITH MATERNAL SMOKING - A MORPHOMETRIC ANALYSIS [J].
COLLINS, MH ;
MOESSINGER, AC ;
KLEINERMAN, J ;
BASSI, J ;
ROSSO, P ;
COLLINS, AM ;
JAMES, LS ;
BLANC, WA .
PEDIATRIC RESEARCH, 1985, 19 (04) :408-412
[8]   Influence of maternal and perinatal factors on subsequent hospitalisation for asthma in children: evidence from the Oxford record linkage study [J].
Davidson, Rebekah ;
Roberts, Stephen E. ;
Wotton, Clare J. ;
Goldacre, Michael J. .
BMC PULMONARY MEDICINE, 2010, 10
[9]   Low maternal vitamin E intake during pregnancy is associated with asthma in 5-year-old children [J].
Devereux, Graham ;
Turner, Stephen W. ;
Craig, Leone C. A. ;
McNeill, Geraldine ;
Martindale, Sheelagh ;
Harbour, Paul J. ;
Helms, Peter J. ;
Seaton, Anthony .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2006, 174 (05) :499-507
[10]   Nutrition as potential determinant of asthma [J].
Devereux, Graham .
PROCEEDINGS OF THE NUTRITION SOCIETY, 2010, 69 (01) :1-10