Increase in the frequency of obstructive sleep apnea in elderly people

被引:31
作者
Ernst, Glenda [1 ,2 ]
Mariani, Javier [1 ]
Blanco, Magali [3 ]
Finn, Barbara [4 ]
Salvado, Alejandro [2 ]
Borsini, Eduardo [2 ,3 ]
机构
[1] Hosp Britanico, Sci Advisory Comm, Buenos Aires, DF, Argentina
[2] Hosp Britanico, Resp Med, Buenos Aires, DF, Argentina
[3] Hosp Britanico, Sleep Unit, Buenos Aires, DF, Argentina
[4] Hosp Britanico, Internal Med, Buenos Aires, DF, Argentina
关键词
Sleep Apnea; Obstructive; Sleep Apnea Syndromes; Adult; Aged; HYPOPNEA; RISK;
D O I
10.5935/1984-0063.20190081
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background: The prevalence of obstructive sleep apnea (OSA) increases with age. However, older adults have limited perception of the symptoms related with poor sleep quality Objectives: To know the frequency and characteristics of age-related OSA in a large population with clinical suspicion of sleep apnea. Methods: We conducted a retrospective study. OSA was studied by respiratory polygraphy (RP). Patients were grouped by age (G): GI was between 18-45; GII: 46-65 and GIII > 65 years old. Other demographic characteristics, symptoms and RP indicators were compared. Epworth Sleep Scale (ESS) was used to analyze symptoms. Results: We included 2491 patients with sleep apnea symptoms. OSA frequency (AHI > 15) in each group was 33.2 % in GI; 45.8 in GII and 50.3 in GIII < 0.001). Despite the significant increase in OSA severity, GIII group reported fewer symptoms (ESS: 6.0;p < 0.001). Multivariate adjusted analysis showed that the odds ratio of having OSA is three times as high at age > 65 (OR: 3.32 (2.29 - 4.88) p < 0.001). Conclusions: As in previous reports, OSA prevalence in our population was higher among the elderly. The early identification of this syndrome in a population with poor perception of symptoms would aid to improve patient management.
引用
收藏
页码:222 / 226
页数:5
相关论文
共 10 条
[1]   Sleep Apnea-Hypopnea Syndrome in the Elderly [J].
Angel Martinez-Garcia, Miguel ;
Duran-Cantolla, Joaquin ;
Maria Montserrat, Jose .
ARCHIVOS DE BRONCONEUMOLOGIA, 2010, 46 (09) :479-488
[2]  
Cohen-Zion M, 2001, J AM GERIATR SOC, V49, P1622, DOI 10.1046/j.1532-5415.2001.t01-1-49270.x
[3]   Pathophysiology of Sleep Apnea [J].
Dempsey, Jerome A. ;
Veasey, Sigrid C. ;
Morgan, Barbara J. ;
O'Donnell, Christopher P. .
PHYSIOLOGICAL REVIEWS, 2010, 90 (01) :47-112
[4]   Obstructive sleep apnea-hypopnea and related clinical features in a population-based sample of subjects aged 30 to 70 yr [J].
Durán, J ;
Esnaola, S ;
Rubio, R ;
Iztueta, A .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2001, 163 (03) :685-689
[5]   Sleep Disordered Breathing with Excessive Daytime Sleepiness is a Risk Factor for Mortality in Older Adults [J].
Gooneratne, Nalaka S. ;
Richards, Kathy C. ;
Joffe, Marshall ;
Lam, Regina W. ;
Pack, Fran ;
Staley, Bethany ;
Dinges, David F. ;
Pack, Allan I. .
SLEEP, 2011, 34 (04) :435-442
[6]   Obstructive Sleep Apnea and Risk of Cardiovascular Events and All-Cause Mortality: A Decade-Long Historical Cohort Study [J].
Kendzerska, Tetyana ;
Gershon, Andrea S. ;
Hawker, Gillian ;
Leung, Richard S. ;
Tomlinson, George .
PLOS MEDICINE, 2014, 11 (02)
[7]   Severe sleep apnea and risk of ischemic stroke in the elderly [J].
Munoz, Roberto ;
Duran-Cantolla, Joaquin ;
Martinez-Vila, Eduardo ;
Gallego, Jaime ;
Rubio, Ramon ;
Aizpuru, Felipe ;
De la Torre, German .
STROKE, 2006, 37 (09) :2317-2321
[8]   Sleep Disorders in the Older Adult - A Mini-Review [J].
Neikrug, Ariel B. ;
Ancoli-Israel, Sonia .
GERONTOLOGY, 2010, 56 (02) :181-189
[9]   Occult Nighttime Hypertension in Daytime Normotensive Older Patients With Obstructive Sleep Apnea [J].
Onen, S. -Hakki ;
Lesourd, Bruno ;
Ouchchane, Lemlih ;
Lin, Jian-Sheng ;
Dubray, Claude ;
Gooneratne, Nalaka S. ;
Onen, Fannie .
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2012, 13 (08) :752-756
[10]   Epidemiology of obstructive sleep apnea - A population health perspective [J].
Young, T ;
Peppard, PE ;
Gottlieb, DJ .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2002, 165 (09) :1217-1239