Heart transplantation in an HIV-infected patient

被引:0
作者
Mouras, Pablo [1 ]
Barcan, Laura [2 ]
Belziti, Cesar [3 ]
Pizarro, Rodolfo [3 ]
Manez, Noelia [2 ]
Marenchino, Ricardo [1 ]
机构
[1] Hosp Italiano Buenos Aires, Serv Cirugia Cardiovasc, Buenos Aires, DF, Argentina
[2] Hosp Italiano Buenos Aires, Serv Clin Med, Secc Infectol, Buenos Aires, DF, Argentina
[3] Hosp Italiano Buenos Aires, Serv Cardiol, Buenos Aires, DF, Argentina
关键词
heart transplantation; HIV; heart failure; RECIPIENTS; CANDIDATES; OUTCOMES; UPDATE; LIVER;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Because of its own unfavourable evolution, HIV infection was until recently considered a contraindication for organ transplantation. The introduction of highly active antiretroviral therapy prolonged the life expectancy of these patients and allowed the manifestation of disorders directly or indirectly related to HIV infection, mainly liver, kidney and cardiovascular diseases. We present a case of cardiac transplantation due to dilated cardiomyopathy that was performed in a patient with a recently detected HIV infection. At 24 month follow-up, the patient is in very good health status, his CD4 are increasing and the viral load is undetectable. He did not present transplant rejection or any other complication. To our knowledge, there is no previous publication on heart transplantation in patients with HIV in South America. In view of the successful outcome of our case and of the few cases reported in the international literature, we consider that heart transplantation is a therapeutic option in correctly selected HIV patients.
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收藏
页码:509 / 511
页数:3
相关论文
共 12 条
[11]   Heart Transplantation in Human Immunodeficiency Virus-Positive Patients [J].
Uriel, Nir ;
Jorde, Ulrich P. ;
Cotarlan, Vlad ;
Colombo, Paolo C. ;
Farr, Maryjane ;
Restaino, Susan W. ;
Lietz, Katherine ;
Naka, Yoshifuma ;
Deng, Mario C. ;
Mancini, Donna .
JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2009, 28 (07) :667-669
[12]   Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naive patients infected with HIV-1 [J].
van Leth, F ;
Phanuphak, P ;
Stroes, E ;
Gazzard, B ;
Cahn, P ;
Raffi, F ;
Wood, R ;
Bloch, M ;
Katlama, C ;
Kastelein, JJP ;
Schechter, M ;
Murphy, RL ;
Horban, A ;
Hall, DB ;
Lange, JMA ;
Reiss, P .
PLOS MEDICINE, 2004, 1 (01) :64-74