Ag2O Nanoparticles as a Candidate for Antimicrobial Compounds of the New Generation

被引：56

作者：

Gudkov, Sergey, V ^{[1
]}

Serov, Dmitriy A. ^{[1
]}

Astashev, Maxim E. ^{[1
]}

Semenova, Anastasia A. ^{[2
]}

Lisitsyn, Andrey B. ^{[2
]}

机构：

[1] Russian Acad Sci, Prokhorov Gen Phys Inst, Moscow 119991, Russia

[2] Russian Acad Sci, VM Gorbatov Fed Res Ctr Food Syst, Moscow 109316, Russia

来源：

PHARMACEUTICALS | 2022年 / 15卷 / 08期

关键词：

silver oxide; nanoparticles; bacteriostatic effect; bactericidal effect; fungistatic effect; fungicidal effect; mammalian cells cytotoxicity; green synthesis; new materials development; SILVER-OXIDE NANOPARTICLES; GREEN SYNTHESIZED SILVER; OVARIAN-CANCER CELLS; SOLVOTHERMAL SYNTHESIS; STAPHYLOCOCCUS-AUREUS; ANTICANCER ACTIVITY; GOLD NANOPARTICLES; RESISTANT BACTERIA; ZNO NANOPARTICLES; ESCHERICHIA-COLI;

D O I：

10.3390/ph15080968

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Antibiotic resistance in microorganisms is an important problem of modern medicine which can be solved by searching for antimicrobial preparations of the new generation. Nanoparticles (NPs) of metals and their oxides are the most promising candidates for the role of such preparations. In the last few years, the number of studies devoted to the antimicrobial properties of silver oxide NPs have been actively growing. Although the total number of such studies is still not very high, it is quickly increasing. Advantages of silver oxide NPs are the relative easiness of production, low cost, high antibacterial and antifungal activities and low cytotoxicity to eukaryotic cells. This review intends to provide readers with the latest information about the antimicrobial properties of silver oxide NPs: sensitive organisms, mechanisms of action on microorganisms and further prospects for improving the antimicrobial properties.

引用

页数：22

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