Lactulose: Production, purification and potential applications

被引:151
作者
Panesar, Parmjit S. [1 ]
Kumari, Shweta [1 ]
机构
[1] St Longowal Inst Engn & Technol, Biotechnol Res Lab, Dept Food Engn & Technol, Longowal 148106, Punjab, India
关键词
Lactulose; Production; Purification; Analysis; Mechanism of action; Applications; INTESTINAL PERMEABILITY; QUANTITATIVE-DETERMINATION; SPECTROPHOTOMETRIC METHOD; YEAST-CELLS; CHROMATOGRAPHIC DETERMINATION; AMPEROMETRIC DETECTION; LACTOSE ISOMERIZATION; LIQUID-CHROMATOGRAPHY; OBSTRUCTIVE-JAUNDICE; SPECTROMETRY METHOD;
D O I
10.1016/j.biotechadv.2011.08.008
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Lactulose a "bifidus factor" is composed of galactose and fructose, which can be produced by the isomerization of lactose. It is a prebiotic carbohydrate which stimulates the growth of health-promoting bacteria in the gastrointestinal tract, such as bifidobacteria and lactobacilli and at the same time inhibits growth of pathogenic bacteria such as Salmonella. It can also be used for the treatment of constipation, hepatic encephalopathy. tumour prevention, and to maintain blood glucose and insulin level. This review provides comprehensive information on the different techniques used for the production of lactulose, purification and analysis. Besides this mechanism of action and its potential applications in food and pharmaceutical industries have also been discussed. (C) 2011 Elsevier Inc. All rights reserved.
引用
收藏
页码:940 / 948
页数:9
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