Dynamic Enantiodivergent Organocatalysis: Merging Molecular Motors with Bifunctional Organocatalysts

被引：0

作者：

Sohtome, Yoshihiro ^{[1
]}

Nagasawa, Kazuo ^{[1
]}

机构：

[1] Tokyo Univ Agr & Technol, Fac Technol, Dept Biotechnol & Life Sci, Koganei, Tokyo 1848588, Japan

来源：

CHEMPHYSCHEM | 2011年 / 12卷 / 12期

关键词：

asymmetric synthesis; enantioswitching; isomerization; molecular motor; organocatalysis; ASYMMETRIC CATALYSIS; MICHAEL ADDITION; BOND DONORS; REVERSAL; SYSTEMS;

D O I：

10.1002/cphc.201100335

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A basic strategy reported by Wang and Feringa for enantiodivergent organocatalysis by exploiting the dynamic stereochemical changes of a molecular motor is described herein. Unidirectional switching of the organocatalytic system can be triggered in situ to produce a racemate, one enantiomer or the other enantiomer of the product of a catalytic carbon-sulfur bond-forming process. © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：2217 / 2219

页数：3