Dynamic Enantiodivergent Organocatalysis: Merging Molecular Motors with Bifunctional Organocatalysts

被引：0
|
作者：
Sohtome, Yoshihiro [1 ]
Nagasawa, Kazuo [1 ]
机构：
[1] Tokyo Univ Agr & Technol, Fac Technol, Dept Biotechnol & Life Sci, Koganei, Tokyo 1848588, Japan
来源：
CHEMPHYSCHEM | 2011年 / 12卷 / 12期
关键词：
asymmetric synthesis; enantioswitching; isomerization; molecular motor; organocatalysis; ASYMMETRIC CATALYSIS; MICHAEL ADDITION; BOND DONORS; REVERSAL; SYSTEMS;
D O I：
10.1002/cphc.201100335
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
A basic strategy reported by Wang and Feringa for enantiodivergent organocatalysis by exploiting the dynamic stereochemical changes of a molecular motor is described herein. Unidirectional switching of the organocatalytic system can be triggered in situ to produce a racemate, one enantiomer or the other enantiomer of the product of a catalytic carbon-sulfur bond-forming process. © 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：2217 / 2219
页数：3
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