Synthesis and Characterization of a Series of Model Complexes of the Active Site of [Fe]-Hydrogenase (Hmd)

被引：37

作者：

Chen, Dafa ^{[1
]}

Ahrens-Botzong, Annegret ^{[2
]}

Schuemann, Volker ^{[2
]}

Scopelliti, Rosario ^{[1
]}

Hu, Xile ^{[1
]}

机构：

[1] Ecole Polytech Fed Lausanne EPFL, Lab Inorgan Synth & Catalysis, Inst Chem Sci & Engn, SBI SICL SCI, CH-1015 Lausanne, Switzerland

[2] Tech Univ Kaiserslautern, Fachbereich Phys, D-67663 Kaiserslautern, Germany

来源：

INORGANIC CHEMISTRY | 2011年 / 50卷 / 11期

基金：

瑞士国家科学基金会;

关键词：

CLUSTER-FREE HYDROGENASE; CRYSTAL-STRUCTURE; IRON HYDROGENASE; 3RD HYDROGENASE; H-2; ACTIVATION; SPECTROSCOPY; MOSSBAUER; REVEALS; LIGANDS; ANALOGS;

D O I：

10.1021/ic200580z

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A series of Fe complexes were synthesized and characterized as small molecule mimics for the active site of [Fe]-hydrogenase (Hmd). The collection includes both structurally new compounds and analogues of previously reported models. These complexes contain the essential ligands of the enzyme, namely, acyl, CO, pyridone, and sulfur ligands. They serve as IR and Mossbauer spectroscopic models for the Fe center in [Fe]-hydrogenase. The field-dependent Mossbauer study of representative model complexes shows that the sign and absolute value of the quadrupole splitting are sensitive to the change in the ligand environment of the Fe center.

引用

页码：5249 / 5257

页数：9

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