Intramolecular cyclization reaction - Palladium(0)-catalyzed cyclization is more effective than tin hydride mediated reaction

被引：32

作者：

Majumdar, Krishna C. ^{[1
]}

Debnath, Pradip ^{[1
]}

Taher, Abu ^{[1
]}

Pal, Amarta K. ^{[1
]}

机构：

[1] Univ Kalyani, Dept Chem, Kalyani 741235, W Bengal, India

来源：

CANADIAN JOURNAL OF CHEMISTRY | 2008年 / 86卷 / 04期

关键词：

Pd(0) catalyst; CH arylation; intramolecular cyclization; regioselectivity;

D O I：

10.1139/V08-023

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Intramolecular CH arylation of pyrone, pyridone, uracil, imidazole, and benzimidazole derivatives are carried out in the presence of a Pd catalyst to form potentially bioactive fused heterocyclic compounds, whereas the n-Bu3SnH-mediated aryl radical cyclization of the precursors 3 afforded mainly halogen-reduced uncyclized products.

引用

页码：325 / 332

页数：8

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