Coronary atherosclerotic lesions in patients with a ruptured abdominal aortic aneurysm

被引:1
|
作者
Nakayama, Atsuko [1 ]
Morita, Hiroyuki [2 ]
Hamamatsu, Akihiko [3 ]
Miyata, Tetsuro [4 ]
Hoshina, Katsuyuki [4 ]
Nagayama, Masatoshi [5 ]
Takanashi, Shuichiro [5 ]
Sumiyoshi, Tetsuya [5 ]
Komuro, Issei [1 ]
机构
[1] Univ Tokyo, Dept Cardiovasc Med, Grad Sch Med, Tokyo 1138655, Japan
[2] Univ Tokyo, Dept Translat Res Healthcare & Clin Sci, Grad Sch Med, Bunkyo Ku, Tokyo 1138655, Japan
[3] Tokyo Med Examiners Off, Tokyo, Japan
[4] Univ Tokyo, Div Vasc Surg, Grad Sch Med, Tokyo 1138655, Japan
[5] Sakakibara Heart Inst, Tokyo, Japan
关键词
Abdominal aortic aneurysm; Rupture; Coronary artery; Left main trunk; Mortality; RISK-FACTORS; REPAIR; ARTERY;
D O I
10.1007/s00380-014-0488-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In this study, the coronary findings in 185 autopsy cases with a ruptured abdominal aortic aneurysm (AAA) from the Tokyo Medical Examiner's Office were examined and compared with those in 1,056 patients undergoing AAA repair at the University of Tokyo Hospital or Sakakibara Heart Institute (Tokyo, Japan). The number of cases with any significant coronary stenosis was significantly greater in the autopsy cases with a ruptured AAA than in the patients undergoing emergency repair of a ruptured AAA, suggesting that the low prevalence of CAD observed in patients undergoing emergency repair of a ruptured AAA was due to the survival bias before reaching hospital. In addition, we also found that significant coronary left main trunk stenosis was more frequent in CAD cases with a ruptured AAA than in those with an unruptured AAA, findings that suggest novel clinical implications. Large-scale prospective studies are warranted to confirm our findings and to clarify the pathophysiological relationship between coronary atherosclerosis and AAA status.
引用
收藏
页码:304 / 308
页数:5
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