The combination of meltblown and electrospinning for bone tissue engineering

被引：34

作者：

Erben, Jakub ^{[1
]}

Pilarova, Katerina ^{[1
]}

Sanetrnik, Filip ^{[1
]}

Chvojka, Jiri ^{[1
]}

Jencova, Vera ^{[1
]}

Blazkova, Lenka ^{[1
]}

Havlicek, Jiri ^{[1
]}

Novak, Ondrej ^{[1
]}

Mikes, Petr ^{[1
]}

Prosecka, Eva ^{[2
]}

Lukas, David ^{[1
]}

Kostakova, Eva Kuzelova ^{[1
]}

机构：

[1] Tech Univ Liberec, Liberec, Czech Republic

[2] Acad Sci, Inst Expt Med, Prague, Czech Republic

来源：

MATERIALS LETTERS | 2015年 / 143卷

关键词：

Meltblown; Electrospinning; Tissue Engineering; Polycaprolactone; FIBERS; DIFFERENTIATION; SCAFFOLDS; SURFACE;

D O I：

10.1016/j.matlet.2014.12.100

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Materials combining meltblown and electrospinning products with hydroxyapatite powder as potential scaffolds for bone tissue engineering are presented here. The combination of these technologies and parameters and final micro-nanofibrous products are introduced too. The in-vitro testing compared meltblown material, meltblown material with sputtered particles, meltblown material combined with electrospun fibers, meltblown material combined with electrospun fibers and sputtered particles. All the fibrous materials are produced from polycaprolactone. The first in-vitro tests showed the high potential of developed composite materials in bone tissue engineering. The structure of the tested materials allows osteoblasts to proliferate into the sample inner structure with the significant contribution of nanofiber content to cell proliferation. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：172 / 176

页数：5

共 21 条

[1] Mimicking Nanofibrous Hybrid Bone Substitute for Mesenchymal Stem Cells Differentiation into Osteogenesis [J].