Carbon fiber reinforced vs titanium implants for fixation in spinal metastases: A comparative clinical study about safety and effectiveness of the new "carbon-strategy"

被引:58
作者
Cofano, Fabio [1 ]
Di Perna, Giuseppe [1 ]
Monticelli, Matteo [1 ]
Marengo, Nicola [1 ]
Ajello, Marco [1 ]
Mammi, Marco [1 ]
Vercelli, Giovanni [1 ]
Petrone, Salvatore [1 ]
Tartara, Fulvio [2 ]
Zenga, Francesco [1 ]
Lanotte, Michele [3 ]
Garbossa, Diego [1 ]
机构
[1] Univ Turin, Dept Neurosci Rita Levi Montalcini, Neurosurg Unit, Via Cherasco 15, I-10126 Turin, Italy
[2] Ist Clin Citta, Neurosurg Unit, Milan, Italy
[3] Univ Turin, Dept Neurosci Rita Levi Montalcini, Stereotact & Funct Neurosurg Unit, Turin, Italy
关键词
Spinal metastases; Carbon fiber screws; Carbon-fiber-reinforced PEEK; Radiotherapy; Scattering effect; SCREWS; TUMORS;
D O I
10.1016/j.jocn.2020.03.013
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
In spinal oncology traditional titanium implants could significantly impair evaluation of postoperative imaging because of artifacts, potentially affecting proper planning and execution of radiotherapy and adequate radiological follow-up to rule out progression of the disease. This is why carbon fiber reinforced (CFR)-PEEK implants have been developed for spinal fixation. The advantages of this system include fewer artifacts on imaging, potentially improving the execution and quality of radiotherapy, with also a reduced scattering effect to neighboring tissues. A comparative clinical and radiological study between new CFR-PEEK and standard titanium implants is described. Data recorded for each case included patient demographics, clinical, radiological and surgical data, intra- and postoperative complications, follow-up information. The goal of this study was to verify the safety and effectiveness of CFR-PEEK devices compared to standard titanium implants. A total number of 78 patients were reviewed. 36 patients underwent CFR-PEEK fixation, while titanium implants were used for 42 patients. Functional recovery was obtained in both groups and registered at last follow-up in terms of axial pain and neurological status. No significative differences were found between the two groups in terms of post-operative clinical complications and hardware-related complications. CFR-PEEK implants constitute a feasible and effective way to restore stability in metastatic spine tumors. This study found a non inferior favorable profile in terms of intraoperative and postoperative complications and functional recovery, compared to titanium. Further prospective studies are needed to clarify the potential oncological advantage of their radiolucency. (C) 2020 Elsevier Ltd. All rights reserved.
引用
收藏
页码:106 / 111
页数:6
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