Non-AIDS comorbidities among people with HIV at a moroccan referral hospital: Prevalence and factors associated with metabolic complications

Background: Among people living with HIV receiving antiretroviral therapy, the prevalence of non-AIDS-related comorbidities is increasing. In Morocco, there are limited dataregarding the profile of non-AIDS comorbidities in this population. The prevalence of non-AIDS comorbidities and the factors associated with metabolic complications among HIV-infected patients are described. Materials and Methods: A cross-sectional study was conducted in 2018 and included 269 HIV-infected patients. A medical officer reviewed records for non-AIDS comorbidities. Univariate and multivariate logistic regression analyses were used to assess the association between metabolic complications and interesting potential variables. Results: A total of 269 individuals were inducted into the study. The mean age was 48.9 +/- 10.7 years and 75.5% were men. The median current CD4+ T-cell count was 613 cells ml-1 (IQR: 390-784 cells ml- 1). More than a third of the patients (34.8%) had at least two non-AIDS comorbidities. The most prevalent comorbidities were hyperlipidemia in 56 (20.8%) patients. In multivariate analysis, older age (odds ratio [OR] = 1.04, 95% confidence interval [CI] = 1.02-1.07) and obesity (OR = 4.25, 95% CI = 1.54-8.74) were associated with the presence of metabolic complications. Conclusions: The prevalence of comorbidities is high, particularly in older people. Care models for HIV-positive patients should include clinical monitoring and effective management of these comorbidities and metabolic complications to complete long-term survival.