Mesenchymal stem cells in the infarcted heart

被引:44
作者
Jain, M
Pfister, O
Hajjar, RJ
Liao, RL
机构
[1] Boston Univ, Sch Med, Whitaker Cardiovasc Inst, Dept Med, Boston, MA 02118 USA
[2] Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Med, Boston, MA 02115 USA
[3] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Cardiovasc Res Ctr, Boston, MA 02115 USA
关键词
mesenchymal stem cells; myocardial regeneration; myocardial infarction; cell therapy;
D O I
10.1097/00019501-200503000-00003
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A loss of functional cardiomyocytes forms the cellular basis of cardiac dysfunction and heart failure. Stem cell based repletion of scarred myocardial tissue and regeneration of cardiomyocytes have been proposed as a potential treatment of ventricular dysfunction. In this review, we provide an overview of recent studies utilizing mesenchymal stem cells in cardiac regeneration and post-myocardial infarct therapy. (c) 2005 Lippincott Williams & Wilkins.
引用
收藏
页码:93 / 97
页数:5
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