Prevention of nephrolithiasis

被引:23
作者
Pearle, MS [1 ]
机构
[1] Univ Texas, SW Med Ctr, Dept Urol, Dallas, TX 75390 USA
关键词
D O I
10.1097/00041552-200103000-00008
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The high incidence of recurrence after an initial stone event underscores the need for an effective medical prophylactic program. Dietary modification and drug therapies have long been advocated to reduce the likelihood of stone recurrence. While the efficacy of a high fluid intake has been validated in a randomized trial, the benefit of other dietary measures is based on modulation of urinary stone risk factors and outcomes derived from observational studies. Several drug therapies have been evaluated in a limited number of prospective, randomized trials and efficacy has been demonstrated for thiazides, allopurinol and alkali citrate in some populations of recurrent stone formers. The role of selective versus nonselective therapy for stone prevention awaits further study. Curr Opin Nephrol Hypertens 10:203-209. (C) 2001 Lippincott Williams & Wilkins.
引用
收藏
页码:203 / 209
页数:7
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