A novel missense mutation in the homeodomain of the hepatocyte nuclear factor-1α/maturity-onset diabetes of the young 3 in a Japanese early-onset type 2 diabetic patient and time-course of glucose-stimulated insulin secretion

被引：12
|
作者：
Awata, T
Kurihara, S
Inoue, K
Inoue, I
Takei, S
Ishii, C
Negishi, K
Namai, K
Kanazawa, Y
Kuzuya, T
Katayama, S
机构：
[1] Saitama Med Sch, Dept Internal Med 4, Moroyama, Saitama 3500495, Japan
[2] Jichi Med Sch, Omiya Med Ctr, Omiya, Saitama, Japan
来源：
DIABETES CARE | 1998年 / 21卷 / 09期
关键词：
D O I：
10.2337/diacare.21.9.1569
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：1569 / 1571
页数：3
相关论文
共 50 条
  • [1] Genetic Study of Hepatocyte Nuclear Factor 1 Alpha Variants in Development of Early-Onset Diabetes Type 2 and Maturity-Onset Diabetes of the Young 3 in Iran
    Mohammadi, Aliasgar
    Eskandari, Ameneh
    Sarmadi, Akram
    Rahimi, Mehrali
    Iraj, Bijan
    Hashemipour, Mahin
    Chaleshtori, Morteza Hashmezadeh
    Tabatabaiefar, Mohammad Amin
    ADVANCED BIOMEDICAL RESEARCH, 2019, 8 (01): : 55
  • [2] Glucose utilization and production in patients with maturity-onset diabetes of the young caused by a mutation of the hepatocyte nuclear factor-1α gene
    Surmely, JF
    Guenat, E
    Philippe, J
    Dussoix, P
    Schneiter, P
    Temler, E
    Vaxillaire, M
    Froguel, P
    Jéquier, E
    Tappy, L
    DIABETES, 1998, 47 (09) : 1459 - 1463
  • [3] A novel dominant-negative mutation of the hepatocyte nuclear factor-1α gene in Japanese early-onset type 2 diabetes
    Tanaka, S
    Kobayashi, T
    Tomura, H
    Okubo, M
    Nakanishi, K
    Takeda, J
    Murase, T
    HORMONE AND METABOLIC RESEARCH, 2000, 32 (09) : 373 - 377
  • [4] Insulin secretion and insulin sensitivity in diabetic and non-diabetic subjects with hepatic nuclear factor-1α (maturity-onset diabetes of the young-3) mutations
    Vaxillaire, M
    Pueyo, ME
    Clément, K
    Fiet, J
    Timsit, J
    Philippe, J
    Robert, JJ
    Tappy, L
    Froguel, P
    Velho, G
    EUROPEAN JOURNAL OF ENDOCRINOLOGY, 1999, 141 (06) : 609 - 618
  • [5] Phenotype of a patient with a de novo mutation in the hepatocyte nuclear factor 1β/maturity-onset diabetes of the young type 5 gene
    Mayer, Christof
    Boettcher, Yvonne
    Kovacs, Peter
    Halbriitter, Jan
    Stumvoll, Michael
    METABOLISM-CLINICAL AND EXPERIMENTAL, 2008, 57 (03): : 416 - 420
  • [6] Mutations in the hepatocyte nuclear factor-1 alpha gene in maturity-onset diabetes of the young (MODY3)
    Yamagata, K
    Oda, N
    Kaisaki, PJ
    Menzel, S
    Furuta, H
    Vaxillaire, M
    Southam, L
    Cox, RD
    Lathrop, GM
    Boriraj, VV
    Chen, XN
    Cox, NJ
    Oda, Y
    Yano, H
    LeBeau, MM
    Yamada, S
    Nishigori, H
    Takeda, J
    Fajans, SS
    Hattersley, AT
    Iwasaki, N
    Hansen, T
    Pedersen, O
    Polonsky, KS
    Turner, RC
    Velho, G
    Chevre, JC
    Froguel, P
    Bell, GI
    NATURE, 1996, 384 (6608) : 455 - 458
  • [7] Mutation in hepatocyte nuclear factor-1α is not a common cause of MODY and early-onset type 2 diabetes in Korea
    H. J. Lee
    C. W. Ahn
    S. J. Kim
    Y. D. Song
    S. K. Lim
    K. R. Kim
    H. C. Lee
    K. B. Huh
    Acta Diabetologica, 2001, 38 : 123 - 127
  • [8] Mutation in hepatocyte nuclear factor-1α is not a common cause of MODY and early-onset type 2 diabetes in Korea
    Lee, HJ
    Ahn, CW
    Kim, SJ
    Song, YD
    Lim, SK
    Kim, KR
    Lee, HC
    Huh, KB
    ACTA DIABETOLOGICA, 2001, 38 (03) : 123 - 127
  • [9] A novel heterozygous mutation in the glucokinase gene is responsible for an early-onset mild form of maturity-onset diabetes of the young, type 2
    Papadimitriou, D. T.
    Willems, P. J.
    Bothou, C.
    Karpathios, T.
    Papadimitriou, A.
    DIABETES & METABOLISM, 2015, 41 (04) : 342 - 343
  • [10] Missense mutations in the human insulin promoter factor-1 gene and their relation to maturity-onset diabetes of the young and late-onset type 2 diabetes mellitus in Caucasians
    Hansen, L
    Urioste, S
    Petersen, HV
    Jensen, JN
    Eiberg, H
    Barbetti, F
    Serup, P
    Hansen, T
    Pedersen, O
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2000, 85 (03): : 1323 - 1326
12345