Recent advances in electrogenerated chemiluminescence biosensing methods for pharmaceuticals

被引：71
|
作者：
Zhang, Yu [1 ]
Zhang, Rui [2 ]
Yang, Xiaolin [3 ]
Qi, Honglan [3 ]
Zhang, Chengxiao [3 ]
机构：
[1] Medpace Bioanalyt Labs, 5365 Medpace Way, Cincinnati, OH 45227 USA
[2] Indiana Univ, Sch Informat Comp & Engn, Bloomington, IN 47405 USA
[3] Shaanxi Normal Univ, Sch Chem & Chem Engn, Key Lab Analyt Chem Life Sci Shaanxi Prov, Xian 710062, Shaanxi, Peoples R China
来源：
JOURNAL OF PHARMACEUTICAL ANALYSIS | 2019年 / 9卷 / 01期
关键词：
Electrogenerated chemiluminescence; Pharmaceutical analysis; Immunoassay; Biosensors; IMPRINTED ELECTROCHEMILUMINESCENCE SENSOR; MULTICENTER ANALYTICAL EVALUATION; CDS QUANTUM DOTS; CARBON NITRIDE; BIOANALYTICAL APPLICATIONS; ULTRASENSITIVE DETECTION; GOLD NANOPARTICLES; MOBILE PHONE; IN-VITRO; IMMUNOASSAY;
D O I：
10.1016/j.jpha.2018.11.004
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Electrogenerated chemiluminescence (electrochemiluminescence, ECL) generates species at electrode surfaces, which undergoes electron-transfer reactions and forms excited states to emit light. It has become a very powerful analytical technique and has been widely used in such as clinical testing, biowarfare agent detection, and pharmaceutical analysis. This review focuses on the current trends of molecular recognition-based biosensing methods for pharmaceutical analysis since 2010. It introduces a background of ECL and presents the recent ECL developments in ECL immunoassay (ECLIA), immunosensors, enzyme-based biosensors, aptamer-based biosensors, and molecularly imprinted polymers (MIP)-based sensors. At last, the future perspective for these analytical methods is briefly discussed. (C) 2018 Xi'an Jiaotong University. Production and hosting by Elsevier B.V.
引用
收藏
页码：9 / 19
页数：11
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