Biphasic paraneoplastic brainstem encephalitis associated with anti-Ri antibody

被引：3

作者：

Tesseki, Kin ^{[1
]}

Kataoka, Hiroshi ^{[1
]}

Terashima, Mari ^{[1
]}

Kawahara, Makoto ^{[1
]}

Taoka, Toshiaki ^{[2
]}

Tanaka, Keiko ^{[3
]}

Ueno, Satoshi ^{[1
]}

机构：

[1] Nara Med Univ, Dept Neurol, Nara 6348522, Japan

[2] Nara Med Univ, Dept Radiol, Nara 6348522, Japan

[3] Kanazawa Med Univ, Dept Neurol, Kanazawa, Ishikawa, Japan

来源：

JOURNAL OF NEURO-ONCOLOGY | 2010年 / 100卷 / 01期

关键词：

Brainstem encephalitis; Anti-Ri antibody; Multiple sclerosis; Breast cancer; MRI;

D O I：

10.1007/s11060-010-0135-7

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Brainstem encephalitis is not a classic paraneoplastic syndrome and usually involves monophasic neurological deterioration and has negative magnetic resonance imaging (MRI) findings. We describe a patient with brainstem encephalitis who had elevated anti-Ri antibody levels and double-step neurological deterioration associated with different abnormal lesions on MRI. Immunosuppression with steroids and intravenous immune globulin combined with aggressive treatment of the tumor successfully led to the resolution of brainstem symptoms and MRI lesions. In patients with unusual signs and symptoms of paraneoplastic encephalitis mimicking multiple sclerosis, onconeural antibody studies are recommended.

引用

页码：141 / 143

页数：3

共 6 条

[1] Cancer risk and impact of disease-modifying treatments in patients with multiple sclerosis [J].