Goal-Directed Resuscitation in Septic Shock: A Critical Analysis

被引：4

作者：

Henning, Daniel J. ^{[1
]}

Shapiro, Nathan I. ^{[2
]}

机构：

[1] Univ Washington, Sch Med, Div Emergency Med, Harborview Med Ctr, 325 9th Ave,Box 359702, Seattle, WA 98104 USA

[2] Harvard Univ, Dept Emergency Med, Beth Israel Deaconess Med Ctr, Sch Med, One Deaconess Rd,W-CC2, Boston, MA 02215 USA

来源：

CLINICS IN CHEST MEDICINE | 2016年 / 37卷 / 02期

关键词：

Severe sepsis; Septic shock; Goal-directed therapy; Resuscitation; PREDICT FLUID RESPONSIVENESS; CENTRAL VENOUS-PRESSURE; VENA-CAVA DIAMETER; SURVIVING SEPSIS CAMPAIGN; LACTATE CLEARANCE; MICROVASCULAR PERFUSION; OXYGEN-SATURATION; VASOACTIVE AGENTS; BLOOD-PRESSURE; ILL PATIENTS;

D O I：

10.1016/j.ccm.2016.01.016

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

The Early Goal-Directed Therapy versus Standard Care for Sepsis trial by Rivers and colleagues in 2001 suggested that a significant mortality reduction may be realized through goal-directed interventions early in the care of patients with septic shock. However, the recent publication of the Protocol-Based Care for Early Septic Shock (ProCESS), Australasian Resuscitation in Sepsis Evaluation (ARISE), and Protocolised Management in Sepsis (ProMISE) trials did not demonstrate the superiority of early goal-directed therapy over usual care. If usual care includes timely and meticulous care, a protocol may not be needed to realize the continued lowering mortality rates.

引用

收藏

页码：231 / +

页数：10

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