Long non-coding RNAs in diabetic wound healing: Current research and clinical relevance

被引：20

作者：

Kuai, Le ^{[1
]}

Jiang, Jing-Si ^{[2
]}

Li, Wei ^{[3
]}

Li, Bin ^{[1
,4
]}

Yin, Shuang-Yi ^{[3
]}

机构：

[1] Shanghai Univ Tradit Chinese Med, Yueyang Hosp Integrated Tradit Chinese & Western, Dept Dermatol, Shanghai, Peoples R China

[2] Shanghai Acad Tradit Chinese Med, Inst Dermatol, Shanghai, Peoples R China

[3] Henan Univ, Ctr Translat Med, Huaihe Hosp, 115 Ximen St, Kaifeng 475001, Henan, Peoples R China

[4] Tongji Univ, Shanghai Skin Dis Hosp, Sch Med, Shanghai, Peoples R China

来源：

INTERNATIONAL WOUND JOURNAL | 2022年 / 19卷 / 03期

基金：

中国国家自然科学基金;

关键词：

diabetes; long non-coding RNA; wound healing; ENDOTHELIAL GROWTH-FACTOR; PERIPHERAL NEUROPATHY; GENE-EXPRESSION; CELL-CYCLE; C-MYC; IGF-I; PROMOTES ANGIOGENESIS; MALAT1; PROLIFERATION; TRANSCRIPTION;

D O I：

10.1111/iwj.13655

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Diabetic wounds are a protracted complication of diabetes mainly characterised by chronic inflammation, obstruction of epithelialization, damaged blood vessels and collagen production (maturation), as well as neuropathy. As a non-coding RNA (ncRNA) that lack coding potential, long non-coding RNAs (lncRNAs) have recently been reported to play a salient role in diabetic wound healing. Here, this review summarises the roles of lncRNAs in the pathology and treatments of diabetic wounds, providing references for its potential clinical diagnostic criteria or therapeutic targets in the future.

引用

页码：583 / 600

页数：18

共 111 条

[1] Effect of Daptomycin on Local Interleukin-6, Matrix Metalloproteinase-9, and Metallopeptidase Inhibitor 1 in Patients With MRSA-Infected Diabetic Foot [J].

Ambrosch, Andreas ;

Halevy, Daniel ;

Fwity, Boushra ;

Brin, Thomas ;

Lobmann, Ralf .

INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS, 2014, 13 (01) :12-16

[2]

[Anonymous], 2021, FASEB J

[3] NF-κB regulates phagocytic NADPH oxidase by inducing the expression of gp91phox [J].

Anrather, J ;

Racchumi, G ;

Iadecola, C .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (09) :5657-5667

[4] A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation [J].

Atianand, Maninjay K. ;

Hu, Wenqian ;

Satpathy, Ansuman T. ;

Shen, Ying ;

Ricci, Emiliano P. ;

Alvarez-Dominguez, Juan R. ;

Bhatta, Ankit ;

Schattgen, Stefan A. ;

McGowan, Jason D. ;

Blin, Juliana ;

Braun, Joerg E. ;

Gandhi, Pallavi ;

Moore, Melissa J. ;

Chang, Howard Y. ;

Lodish, Harvey F. ;

Caffrey, Daniel R. ;

Fitzgerald, Katherine A. .

CELL, 2016, 165 (07) :1672-1685

[5] Epigenetic control of adult stem cell function [J].

Avgustinova, Alexandra ;

Benitah, Salvador Aznar .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2016, 17 (10) :643-658

[6] A novel ATAC-seq approach reveals lineage-specific reinforcement of the open chromatin landscape via cooperation between BAF and p63 [J].

Bao, Xiaomin ;

Rubin, Adam J. ;

Qu, Kun ;

Zhang, Jiajing ;

Giresi, Paul G. ;

Chang, Howard Y. ;

Khavari, Paul A. .

GENOME BIOLOGY, 2015, 16

[7] ACTL6a Enforces the Epidermal Progenitor State by Suppressing SWI/SNF-Dependent Induction of KLF4 [J].

Bao, Xiaomin ;

Tang, Jiong ;

Lopez-Pajares, Vanessa ;

Tao, Shiying ;

Qu, Kun ;

Crabtree, Gerald R. ;

Khavari, Paul A. .

CELL STEM CELL, 2013, 12 (02) :193-203

[8] Preventing and treating foot complications associated with diabetes mellitus [J].

Bowling, Frank L. ;

Rashid, S. Tawqeer ;

Boulton, Andrew J. M. .

NATURE REVIEWS ENDOCRINOLOGY, 2015, 11 (10) :606-616

[9] E2F target genes: unraveling the biology [J].

Bracken, AP ;

Ciro, M ;

Cocito, A ;

Helin, K .

TRENDS IN BIOCHEMICAL SCIENCES, 2004, 29 (08) :409-417

[10] A genome-wide long noncoding RNA CRISPRi screen identifies PRANCR as a novel regulator of epidermal homeostasis [J].

Cai, Pengfei ;

Otten, Auke B. C. ;

Cheng, Binbin ;

Ishii, Mitsuhiro A. ;

Zhang, Wen ;

Huang, Beibei ;

Qu, Kun ;

Sun, Bryan K. .

GENOME RESEARCH, 2020, 30 (01) :22-34

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