Early neonatal brain injury in histologic chorioamnionitis

被引:118
作者
De Felice, C
Toti, P
Laurini, RN
Stumpo, M
Picciolini, E
Todros, T
Tanganelli, P
Buonocore, G
Bracci, R
机构
[1] Univ Siena, Dept Prevent Pediat & Neonatol, I-53100 Siena, Italy
[2] Univ Siena, Inst Pathol, I-53100 Siena, Italy
[3] Univ Siena, Dept Obstet & Gynecol, I-53100 Siena, Italy
[4] Univ Turin, Div Fetomaternal Med, Turin, Italy
[5] Univ Lausanne, Div Dev Pathol, Lausanne, Switzerland
关键词
D O I
10.1067/mpd.2001.109605
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The relation between clinical or histologic chorioamnionitis and early neonatal adverse neurologic outcome was investigated (n = 483). Histologic, but not clinical, evidence of chorioamnionitis was found to be a significant predictor of per;ventricular echodensity (odds ratio, 2.4; 95% CI, 1.8-3.2), echolucency (3.3; 1.9-5.6), ventriculomegaly (2.7; 1.8-4.2), intraventricular hemorrhage greater than or equal to3 (3.5; 2.4-5.2), and seizures (2.3; 1.4-3.7).
引用
收藏
页码:101 / 104
页数:4
相关论文
共 19 条
  • [1] Role of the placenta in perinatal pathology (revisited)
    Altshuler, G
    [J]. PEDIATRIC PATHOLOGY & LABORATORY MEDICINE, 1996, 16 (02): : 207 - 233
  • [2] Placental histology and clinical characteristics of patients with preterm premature rupture of membranes
    Arias, F
    Victoria, A
    Cho, K
    Kraus, F
    [J]. OBSTETRICS AND GYNECOLOGY, 1997, 89 (02) : 265 - 271
  • [3] Amniotic fluid concentrations of Interleukin-1β, Interleukin-6 and TNF-α in chorioamnionitis before 32 weeks of gestation:: histological associations and neonatal outcome
    Baud, O
    Emilie, D
    Pelletier, E
    Lacaze-Masmonteil, T
    Zupan, V
    Fernandez, H
    Dehan, M
    Frydman, R
    Ville, Y
    [J]. BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1999, 106 (01): : 72 - 77
  • [4] Intrauterine infection, cytokines, and brain damage in the preterm newborn
    Dammann, O
    Leviton, A
    [J]. PEDIATRIC RESEARCH, 1997, 42 (01) : 1 - 8
  • [5] Small thymus in very low birth weight infants born to mothers with subclinical chorioamnionitis
    De Felice, C
    Toti, P
    Santopietro, R
    Stumpo, M
    Pecciarini, L
    Bagnoli, F
    [J]. JOURNAL OF PEDIATRICS, 1999, 135 (03) : 384 - 386
  • [6] THE SPECTRUM OF LEUKOMALACIA USING CRANIAL ULTRASOUND
    DEVRIES, LS
    EKEN, P
    DUBOWITZ, LMS
    [J]. BEHAVIOURAL BRAIN RESEARCH, 1992, 49 (01) : 1 - 6
  • [7] The fetal inflammatory response syndrome
    Gomez, R
    Romero, R
    Ghezzi, F
    Yoon, BH
    Mazor, M
    Berry, SM
    [J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1998, 179 (01) : 194 - 202
  • [8] Maternal infection and cerebral palsy in infants of normal birth weight
    Grether, JK
    Nelson, KB
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1997, 278 (03): : 207 - 211
  • [9] HOBEL C, 1992, PERINATOLOGY, V26, P111
  • [10] Inder T E, 2000, Semin Neonatol, V5, P3, DOI 10.1053/siny.1999.0112